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논문 기본 정보

자료유형
학술저널
저자정보
Hyeong Ho Jo (Department of Internal Medicine Daegu Catholic University School of Medicine Daegu Korea) Eun Young Kim (Department of Internal Medicine Daegu Catholic University School of Medicine Daegu Korea) Jin Tae Jung (Department of Internal Medicine Daegu Catholic University School of Medicine Daegu Korea) Joong Goo Kwon (Department of Internal Medicine Daegu Catholic University School of Medicine Daegu Korea) Eun Soo Kim (Department of Internal Medicine School of Medicine Kyungpook National University Daegu Korea) Hyun Seok Lee (Department of Internal Medicine School of Medicine Kyungpook National University Daegu Korea) Yoo Jin Lee (Department of Internal Medicine Keimyung University School of Medicine Daegu Korea) Kyeong Ok Kim (Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea) Byung Ik Jang (Department of Internal Medicine Yeungnam University College of Medicine Daegu Korea)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy 제55권 제2호
발행연도
2022.3
수록면
256 - 262 (7page)
DOI
10.5946/ce.2021.061

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Background/Aims: The diagnosis of intestinal tuberculosis (ITB) is often challenging. Therapeutic anti-tubercular trial (TATT) issometimes used for the diagnosis of ITB. We aimed to evaluate the changing pattern of fecal calprotectin (FC) levels during TATT inpatients with ITB. Methods: A retrospective review was performed on the data of 39 patients who underwent TATT between September 2015 andNovember 2018 in five university hospitals in Daegu, South Korea. The analysis was performed for 33 patients with serial FCmeasurement reports. Results: The mean age of the participants was 48.8 years. The final diagnosis of ITB was confirmed in 30 patients based on completemucosal healing on follow-up colonoscopy performed after 2 months of TATT. Before starting TATT, the mean FC level of the ITBpatients was 170.2 μg/g (range, 11.5-646.5). It dropped to 25.4 μg/g (range, 11.5-75.3) and then 23.3 μg/g (range, 11.5-172.2) afterone and two months of TATT, respectively. The difference in mean FC before and one month after TATT was statistically significant(p<0.001), and FC levels decreased to below 100 μg/g in all patients after one month of TATT. Conclusions: All ITB patients showed FC decline after only 1 month of TATT, and this finding correlated with complete mucosalhealing in the follow-up colonoscopy after 2 months of TATT.

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