지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 53 - 57 (5page)
이용수
초록· 키워드
오류제보하기
Clostridium difficile is a significant nosocomial and community-acquired pathogen, and is the leading cause of antibiotic-induced diarrhea associated with high morbidity and mortality. Given that the treatment outcome depends on the severity of C. difficile infection (CDI), we aimed to establish an efficient method of assessing severity, and focused on the stool biomarker fecal calprotectin (FC). FC directly reflects the intestinal inflammation status of a patient, and can aid in interpreting the current guidelines, which requires the integration of indirect laboratory parameters. The distinction of 80 patients with CDI versus 71 healthy controls and 30 severe infection cases versus 50 mild cases was possible using FC as a marker. The area under the receiver operating characteristic curves were 0.821 and 0.746 with a sensitivity of 75% and 70% and specificity of 79% and 80%, for severe versus mild cases, respectively. We suggest FC as a predictive marker for assessing CDI severity, which is expected to improve the clinical management of CDI.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Aradhyula S / 2006 / Significant absorption of oral vancomycin in a patient with Clostridium difficile colitis and normal renal function / South Med J 99 : 518 ~ 520
Boone JH / 2013 / Elevated lactoferrin is associated with moderate to severe Clostridium difficile disease, stool toxin, and 027 infection / Eur J Clin Microbiol Infect Dis 3
Caccaro R / 2010 / Clinical utility of calprotectin and lactoferrin as markers of inflammation in patients with inflammatory bowel disease / Expert Rev Clin Immunol 6 : 551
Cohen SH / 2010 / Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the
Crobach MJ / 2009 / European Society of Clinical Microbiology and Infectious Diseases (ESCMID): data review and recommendations for diagnosing Clostridium difficile-infectio
Boone JH / 2013 / Elevated lactoferrin is associated with moderate to severe Clostridium difficile disease, stool toxin, and 027 infection / Eur J Clin Microbiol Infect Dis 3
Caccaro R / 2010 / Clinical utility of calprotectin and lactoferrin as markers of inflammation in patients with inflammatory bowel disease / Expert Rev Clin Immunol 6 : 551
Cohen SH / 2010 / Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the
Crobach MJ / 2009 / European Society of Clinical Microbiology and Infectious Diseases (ESCMID): data review and recommendations for diagnosing Clostridium difficile-infectio
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Detection and characterization of Clostridium difficile infections tracking the trends of Clostridium difficile culture
한국의료질향상학회지
2016 .01
-
급성기 의료기관의 C. difficile 감염관리 전략과 전망
의료관련감염관리
2021 .12
-
노인층에서 Clostridium difficile 감염 약물사용평가 및 비호전군에 대한 영향인자
한국임상약학회지
2018 .01
-
Laboratory diagnosis of Clostridioides difficile infection: guidelines and status of practice in Korea
Annals of Clinical Microbiology
2024 .03
-
The impact of corticosteroid use on inpatients with inflammatory bowel disease and positive polymerase chain reaction for Clostridium difficile
Intestinal research
2019 .01
-
Clinical and Microbiological Risk Factors for Community-Associated Clostridioides difficile Infections
Annals of Clinical Microbiology
2022 .06
-
Fecal Transplantation using a Nasoenteric Tube during an Initial Episode of Severe Clostridium difficile Infection
Infection and Chemotherapy
2016 .01
-
소아 Clostridioides difficile 감염의 발생률 및 임상양상
Pediatric Infection and Vaccine
2020 .01
-
Incidence of Clostridioides difficile Infections in Republic of Korea: A Prospective Study With Active Surveillance vs. National Data From Health Insurance Review & Assessment Service
Journal of Korean Medical Science
2024 .04
-
A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation
Gut and Liver
2015 .01
-
Risk of Clostridium difficile Infection with the Use of a Proton Pump Inhibitor for Stress Ulcer Prophylaxis in Critically Ill Patients
Gut and Liver
2016 .01
-
Clostridioides (Clostridium) difficile 감염에서 대변 Neutrophil Gelatinase-Associated Lipocalin과 Calprotectin의 생물학적 표지자로서의 임상적 유용성
Laboratory Medicine Online
2020 .01
-
Clostridium difficile 감염증 진단을 위한 검사법의 비교 평가
Laboratory Medicine Online
2017 .01
-
Clostridium difficile Infection After Ileostomy Reversal
Annals of Coloproctology
2021 .01
-
Association between Antibiotic Consumption and Incidence of Clostridioides difficile Infection in a Hospital
Journal of Korean Medical Science
2020 .01
-
장질환에 있어서 Fecal Calprotectin의 적절한 사용
대한내과학회지
2018 .01
-
Treatment Options For C. Difficile Infection
대한외과학회 학술대회 초록집
2017 .11
-
Nationwide Survey for Current Status of Laboratory Diagnosis of Clostridioides difficile Infection in Korea
Journal of Korean Medical Science
2022 .02
-
Fecal Calprotectin and Phenotype Severity in Patients with Cystic Fibrosis: A Systematic Review and Meta-Analysis
Pediatric Gastroenterology, Hepatology & Nutrition
2022 .01
-
Clostridioides difficile Infection Is Associated with Adverse Outcomes among Hospitalized Pediatric Patients with Acute Pancreatitis
Pediatric Gastroenterology, Hepatology & Nutrition
2022 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0