지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.7
- 수록면
- 406 - 414 (9page)
- DOI
- 10.3343/alm.2022.42.4.406
이용수
초록· 키워드
오류제보하기
Background: Biomarkers and clinical indices have been investigated for predicting mortality in patients with coronavirus disease (COVID-19). We explored the prognostic utility of procalcitonin (PCT), presepsin, and the Veterans Health Administration COVID-19 (VACO) index for predicting 30-day-mortality in COVID-19 patients.
Methods: In total, 54 hospitalized COVID-19 patients were enrolled. PCT and presepsin levels were measured using the Elecsys BRAHMS PCT assay (Roche Diagnostics GmbH, Mannheim, Germany) and HISCL Presepsin assay (Sysmex, Kobe, Japan), respectively. The VACO index was calculated based on age, sex, and comorbidities. PCT and presepsin levels and the VACO index were compared using ROC curve, Kaplan?Meier method, and reclassification analysis for the 30-day mortality.
Results: ROC curve analysis was used to measure PCT and presepsin levels and the VACO index to predict 30-day mortality; the optimal cut-off values were 0.138 ng/mL for PCT, 717 pg/mL for presepsin, and 12.1% for the VACO index. On Kaplan?Meier survival analysis, hazard ratios (95% confidence interval) were 15.9 (4.1-61.3) for PCT, 26.3 (6.4-108.0) for presepsin, and 6.0 (1.7-21.1) for the VACO index. On reclassification analysis, PCT and presepsin in addition to the VACO index significantly improved the prognostic value of the index.
Conclusions: This study demonstrated the prognostic utility of measuring PCT and presepsin levels and the VACO index in COVID-19 patients. The biomarkers in addition to the clinical index were more useful than the index alone for predicting clinical outcomes in COVID-19 patients.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
No Significant Differences in Presepsin Levels According to the Causative Microorganism of Bloodstream Infection
Infection and Chemotherapy
2024 .03
-
Presepsin 검사의 검체 안정성 평가
Laboratory Medicine Online
2024 .04
-
Usefulness of presepsin in predicting the prognosis of patients with sepsis or septic shock: a retrospective cohort study
Journal of Yeungnam Medical Science
2021 .10
-
Plasma presepsin for mortality prediction in patients with sepsis-associated acute kidney injury requiring continuous kidney replacement therapy
Kidney Research and Clinical Practice
2024 .07
-
Prediction of Postoperative Sepsis Using Change of Presepsin Level in Surgical Intensive Care Unit Patients With Acute Kidney Injury After Abdominal Surgery
대한외과학회 학술대회 초록집
2021 .11
-
소아 폐렴 환자에서 혈중 procalcitonin을 이용한 항생제 사용 결정과 임상적 결과의 비교 분석
Allergy Asthma & Respiratory Diseases
2016 .01
-
Predictive Value of Procalcitonin for Infection and Survival in Adult Cardiogenic Shock Patients Treated with Extracorporeal Membrane Oxygenation
전남의대학술지
2018 .01
-
Diagnosis and prediction of periodontally compromised teeth using a deep learning-based convolutional neural network algorithm
Journal of Periodontal & Implant Science
2018 .01
-
[Trauma/Critical Care/Emergency Surgery] Predictive Role of Changes in Postoperative Presepsin Level and Early Postoperative Sepsis in Intensive Care Unit Patients after Abdominal Surgery
대한외과학회 학술대회 초록집
2021 .11
-
Clinical Usefulness of Procalcitonin as a Predictive Marker in Accordance with the Severity of Female Patients with Uncomplicated Acute Pyelonephritis
Urogenital Tract Infection
2016 .01
-
Diagnostic value of procalcitonin and CRP in critically ill patients admitted with suspected sepsis
Journal of dental anesthesia and pain medicine
2015 .01
-
산소 치료가 필요한 COVID-19 노인 환자의 특성
임상노인의학회지
2021 .12
-
아세트아미노펜 중독 청소년에서의 프로칼시토닌 상승
대한임상독성학회지
2019 .01
-
Prognostic Value of Serum Procalcitonin level for the Diagnosis of Bacterial Infections in Critically-ill Patients
Infection and Chemotherapy
2019 .01
-
Value of procalcitonin as a biomarker for postoperative hospital-acquired pneumonia after abdominal surgery
Korean Journal of Anesthesiology
2017 .01
-
Implementation of Procalcitonin in Antibiotic Stewardship: Derivation of a Consensus Algorithm for Procalcitonin Use in Clinical Practice
Infection and Chemotherapy
2022 .12
-
Association Between High Platelet Indices and Proteinuria in Patients With Hypertension
Annals of Laboratory Medicine
2015 .01
-
Diagnostic value of presepsin in odontogenic infection: a retrospective study
Maxillofacial Plastic Reconstructive Surgery
2022 .01
-
Serum Procalcitonin as a Useful Serologic Marker for Differential Diagnosis between Acute Gouty Attack and Bacterial Infection
Yonsei Medical Journal
2016 .01
-
Serum procalcitonin and C-reactive protein as indices of early sepsis and mortality in North Indian pediatric burn injuries: a prospective evaluation and literature review
Acute and Critical Care
2024 .08
이 논문의 저자 정보
최근 본 자료
댓글(0)
0