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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Procalcitonin (PCT) is a predictive marker for the occurrence of bacterial infection andthe decision to terminate antibiotic treatment in critically ill patients. An unusual increasein PCT, regardless of infection, has been observed during extracorporeal membraneoxygenation (ECMO) support. We evaluated trends and the predictive value ofPCT levels in adult cardiogenic shock during treatment with ECMO. We reviewed theclinical records of 38 adult cardiogenic shock patients undergoing veno-arterial ECMOsupport between January 2014 and December 2016. The exclusion criteria were age＜18 years, pre-ECMO infection, and less than 48 hours of support. The mean patientage was 56.7±14.7 years and 12 (31.6%) patients were female. The mean duration ofECMO support was 9.0±7.6 days. The rates of successful ECMO weaning and survivalto discharge were 55.3% (n=21) and 52.6% (n=20), respectively. There were 17 nosocomialinfections in 16 (42.1%) patients. Peak PCT levels (mean 25.6±9.4 ng/mL) werereached within 48 hours after initiation of ECMO support and decreased to ≤5 ng/mLwithin one week. The change in PCT levels was not useful in predicting the occurrenceof new nosocomial infections during the ECMO run. However, a PCT level ＞10 ng/mLduring the first week of ECMO support was significantly associated with mortality (p＜0.01). The change in PCT level was not useful in predicting new infection duringECMO support. However, higher PCT levels within the first week of the ECMO runare associated with significantly higher mortality.
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참고문헌 (26)
참고문헌 신청
조화진 / 2017 / Anticoagulation Therapy during Extracorporeal Membrane Oxygenator Support in Pediatric Patients / 전남의대학술지 53(2):110~117
Bizzarro MJ / 2011 / Infections acquired during extracorporeal membrane oxygenation in neonates, children, and adults / Pediatr Crit Care Med 12:277~281
Sandkovsky U / 2015 / The use and value of procalcitonin in solid organ transplantation / Clin Transplant 29:689~696
Cosse C / 2017 / Impact of a procalcitonin-based algorithm on the management of adhesion-related small bowel obstruction / J Visc Surg 154:231~237
Cosse C / 2014 / Procalcitonin and intestinal ischemia: a review of the literature / World J Gastroenterol 20:17773~17778
Bizzarro MJ / 2011 / Infections acquired during extracorporeal membrane oxygenation in neonates, children, and adults / Pediatr Crit Care Med 12:277~281
Sandkovsky U / 2015 / The use and value of procalcitonin in solid organ transplantation / Clin Transplant 29:689~696
Cosse C / 2017 / Impact of a procalcitonin-based algorithm on the management of adhesion-related small bowel obstruction / J Visc Surg 154:231~237
Cosse C / 2014 / Procalcitonin and intestinal ischemia: a review of the literature / World J Gastroenterol 20:17773~17778
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