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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Purine catabolite screening enables reliable diagnosis of certain diseases. In this regard, the development of a facile detection strategy with high sensitivity and selectivity is demanded for pointof-care applications. In this work, the simultaneous detection of uric acid (UA), xanthine (XA), and hypoxanthine (HX) was carried out as model purine catabolites by surface-enhanced Raman Spectroscopy (SERS). The detection assay was conducted by employing high-aspect ratio Au nanopillar substrates coupled with in-situ Au electrodeposition on the substrates. The additional modification of the Au nanopillar substrates via electrodeposition was found to be an effective method to encapsulate molecules in solution into nanogaps of growing Au films that increase metal-molecule contact and improve substrate’s sensitivity and selectivity. In complex solutions, the approach facilitated ternary identification of UA, XA, and HX down to concentration limits of 4.33 μM, 0.71 μM, and 0.22 μM, respectively, which are comparable to their existing levels in normal human physiology. These results demonstrate that the proposed platform is reliable for practical point-of-care analysis of biofluids where solution matrix effects greatly reduce selectivity and sensitivity for rapid on-site disease diagnosis.
목차
Abstract
1. Introduction
2. Experimental Section
3. Results and discussion
4. Conclusion
References
참고문헌 (40)
참고문헌 신청
D. Cialla, A. März, R. Böhme, F. Theil, K. Weber, M. Schmitt, J. Popp, Surfaceenhanced raman spectroscopy (SERS): progress and trends, Anal. Bioanal. Chem., 403(2012) 27-54.
S. Kim, I. B. Ansah, J. S. Park, H. Dang, N. Choi, W. C. Lee, S. H. Lee, H. S. Jung, D. H. Kim, S. M. Yoo, J. Choo, S. H. Kim, S. G. Park, Early and direct detection of bacterial signaling molecules through one-pot Au electrodeposition onto paper-based 3D SERS substrates, Sens. Actuators B Chem., 358(2022) 131504.
E. H. Koh, W. C. Lee, Y. J. Choi, J. I. Moon, J. Jang, S. G. Park, J. Choo, D. H. Kim, H. S. Jung, A wearable surface-enhanced raman scattering sensor for label-free molecular detection, ACS Appl. Mater. Interfaces, 13(2021) 3024-3032.
C. Li , Y. Huang, X. Li, Y. Zhang, Q. Chen, Z. Ye, Z. Alqarni, S. E. J. Bell, Y. Xu, Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates, J. Mater. Chem. C, 9(2021) 11517-11552.
V. T. N. Linh, J. Moon, C. W. Mun, V. Devaraj, J. W. Oh, S. G. Park, D. H. Kim, J. Choo, Y. I. Lee, H. S. Jung, A facile lowcost paper-based SERS substrate for labelfree molecular detection, Sens. Actuators B Chem., 291(2019) 369-377.
S. Kim, I. B. Ansah, J. S. Park, H. Dang, N. Choi, W. C. Lee, S. H. Lee, H. S. Jung, D. H. Kim, S. M. Yoo, J. Choo, S. H. Kim, S. G. Park, Early and direct detection of bacterial signaling molecules through one-pot Au electrodeposition onto paper-based 3D SERS substrates, Sens. Actuators B Chem., 358(2022) 131504.
E. H. Koh, W. C. Lee, Y. J. Choi, J. I. Moon, J. Jang, S. G. Park, J. Choo, D. H. Kim, H. S. Jung, A wearable surface-enhanced raman scattering sensor for label-free molecular detection, ACS Appl. Mater. Interfaces, 13(2021) 3024-3032.
C. Li , Y. Huang, X. Li, Y. Zhang, Q. Chen, Z. Ye, Z. Alqarni, S. E. J. Bell, Y. Xu, Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates, J. Mater. Chem. C, 9(2021) 11517-11552.
V. T. N. Linh, J. Moon, C. W. Mun, V. Devaraj, J. W. Oh, S. G. Park, D. H. Kim, J. Choo, Y. I. Lee, H. S. Jung, A facile lowcost paper-based SERS substrate for labelfree molecular detection, Sens. Actuators B Chem., 291(2019) 369-377.
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