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논문 기본 정보

자료유형
학술저널
저자정보
Hyejin Cho (Chung-Ang University) Ki Hyun Kim (Sungkyunkwan University) Sin Hee Han (Rural Development Administration) Hak-Jae Kim (Soonchunhyang University) Ik-Hyun Cho (Kyung Hee University) Sanghyun Lee (Chung-Ang University)
저널정보
한국생약학회 Natural Product Sciences Natural Product Sciences Vol.28 No.4
발행연도
2022.12
수록면
181 - 186 (6page)
DOI
10.20307/nps.2022.28.4.181

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초록· 키워드

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A germacrane-type sesquiterpenoid was isolated and purified from a methanol extract of the roots of Valeriana fauriei (RVF) through open column chromatography using silica gel. This compound was verified to be heishuixiecaoline A by spectroscopic analysis. This compound was isolated for the first time from RVF. Quantitative analysis of heishuixiecaoline A from RVF cultivated from three different regions (Eumseong, Jinbu, and Jinan regions) was performed by combining high-performance liquid chromatography with a photodiode array detector. The extract of RVF cultivated in the Jinbu region showed the highest content (9.23 mg/g). In addition, a significant amount of the compound was detected in all RVF samples, which could be expected since it is a characteristic compound of RVF. The sesquiterpenoid group heishuixiecaoline A was isolated from RVF, a resource for various pharmacological substances, and quantitative analysis of RVF cultivated from three different regions was performed. As a result of these experiments, basic data on RVF that can be used in the development and application of pharmaceuticals and health functional foods in the future were obtained.

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Abstract
Introduction
Experimental
Results and Discussion
References

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