지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.102 No.2
- 발행연도
- 2022.2
- 수록면
- 73 - 82 (10page)
이용수
초록· 키워드
오류제보하기
Purpose: Long-term safety of pregnancy after breast cancer (BC) remains controversial, especially with respect to BC biological subtypes.
Methods: We analyzed a population-based retrospective cohort with BC from 2002 to 2017. Patient-level 1:1 matching was performed between pregnant and nonpregnant women. The study population was categorized into 6 biological subtypes based on the combination of prescribed therapies. Subanalyses were performed considering the time to pregnancy after BC diagnosis, systemic therapy, and pregnancy outcomes.
Results: We identified 544 matched women with BC, who were assigned to the pregnant (cases, n = 272) or nonpregnant group (controls, n = 272) of similar characteristics, adjusted for guaranteed bias. These patients were followed up for 10 years, or disease and mortality occurrence after the diagnosis of BC. Survival estimates were calculated. The actuarial 10-year overall survival (OS) rates were 97.4% and 91.9% for pregnant and nonpregnant patients, respectively. The pregnant group showed significantly better OS (adjusted hazard ratio [aHR], 0.29; 95% confidence interval [CI], 0.12–0.68; P = 0.005) and did not have a significantly inferior disease-free survival (aHR, 1.10; 95% CI, 0.61–1.99; P = 0.760).
Conclusion: Consistent outcomes were observed in every subgroup analysis. Our observational data provides reassuring evidence on the long-term safety of pregnancy in young patients with BC regardless of the BC biological subtype.
Methods: We analyzed a population-based retrospective cohort with BC from 2002 to 2017. Patient-level 1:1 matching was performed between pregnant and nonpregnant women. The study population was categorized into 6 biological subtypes based on the combination of prescribed therapies. Subanalyses were performed considering the time to pregnancy after BC diagnosis, systemic therapy, and pregnancy outcomes.
Results: We identified 544 matched women with BC, who were assigned to the pregnant (cases, n = 272) or nonpregnant group (controls, n = 272) of similar characteristics, adjusted for guaranteed bias. These patients were followed up for 10 years, or disease and mortality occurrence after the diagnosis of BC. Survival estimates were calculated. The actuarial 10-year overall survival (OS) rates were 97.4% and 91.9% for pregnant and nonpregnant patients, respectively. The pregnant group showed significantly better OS (adjusted hazard ratio [aHR], 0.29; 95% confidence interval [CI], 0.12–0.68; P = 0.005) and did not have a significantly inferior disease-free survival (aHR, 1.10; 95% CI, 0.61–1.99; P = 0.760).
Conclusion: Consistent outcomes were observed in every subgroup analysis. Our observational data provides reassuring evidence on the long-term safety of pregnancy in young patients with BC regardless of the BC biological subtype.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Comparison of Oncoplastic Breast-Conserving Surgery and Breast- Conserving Surgery Alone: A Meta-Analysis
Journal of Breast Cancer
2018 .01
-
Oncologic safety of breast-conserving surgery in breast cancer patients under the age of 35
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2017 .06
-
The Clinical Impact of Body Mass Index on Breast Cancer in Korea: A Nationwide Population-Based Cohort Study
Journal of Breast Disease
2020 .01
-
Pregnancy After Breast Cancer – Prognostic Safety and Pregnancy Outcomes According to Oestrogen Receptor Status: A Systematic Review
Journal of Breast Cancer
2022 .12
-
고위험 임신의 외래 산전진찰시 고려사항
Perinatology
2023 .06
-
13 Cases of Pregnancy-associated breast cancer
대한외과학회 학술대회 초록집
2019 .10
-
Comparison of Long-Term Oncological Outcomes in Oncoplastic Breast Surgery and Conventional Breast-Conserving Surgery for Breast Cancer: A Propensity Score-Matched Analysis
Journal of Breast Cancer
2021 .12
-
Are the Outcomes of Breast Conservation Surgery Inferior to Those of Mastectomy in Patients with Stage II-IIIA Triple-Negative Breast Cancer?
Journal of Breast Disease
2021 .12
-
The Association Between Smoking Status and Breast Cancer Recurrence: A Systematic Review
Journal of Breast Cancer
2022 .08
-
COL6A1 expression as a potential prognostic biomarker for risk stratification of T1 high grade bladder cancer: Unveiling the aggressive nature of a distinct non-muscle invasive subtype
Investigative and Clinical Urology
2024 .01
-
Weight Gain and Alcohol Drinking Associations with Breast Cancer Risk in Japanese Postmenopausal Women - Results from the Japan Collaborative Cohort (JACC) Study
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Parity and Survival in Pregnancy Associated Breast Cancer Patients
대한외과학회 학술대회 초록집
2018 .11
-
Breast Cancer Awareness at the Community Level among Women in Delhi, India
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Outcomes of Pregnancy after Breast Cancer in Korean Women: A Large Cohort Study
Cancer Research and Treatment
2020 .01
-
Risk Reduction of Breast Cancer by Childbirth, Breastfeeding, and Their Interaction in Korean Women: Heterogeneous Effects Across Menopausal Status, Hormone Receptor Status, and Pathological Subtypes
예방의학회지
2017 .01
-
Clinical characteristics and outcome of cancer diagnosed during pregnancy
Obstetrics & Gynecology Science
2016 .01
-
Dietary Resistant Starch Contained Foods and Breast Cancer Risk: a Case-Control Study in Northwest of Iran
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Upregulated N6-Methyladenosine RNA in Peripheral Blood: Potential Diagnostic Biomarker for Breast Cancer
Cancer Research and Treatment
2021 .01
-
Survival of Pregnancy-Associated Breast Cancer according to the Clinical Characteristics: A Propensity Score Matching Study
대한외과학회 학술대회 초록집
2020 .11
-
유방보존술 후 흡수성 메쉬 삽입에 대한 결과와 환자의 만족도
Journal of Breast Disease
2017 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-514-000221233