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자료유형
학술저널
저자정보
Muna Alkhaifi (Department of Family and Community Medicine St. Michael’s Hospital Unity Health Toronto Faculty of) Adam Clayton (Faculty of Medicine University of Toronto Toronto Canada.) Teruko Kishibe (Library Services St. Michael Hospital Unity Health Toronto Toronto Canada.) Jory S Simpson (Division of General Surgery Department of Surgery St. Michael’s Hospital Unity Health Toronto Facul)
저널정보
한국유방암학회 Journal of Breast Cancer Journal of Breast Cancer Vol.25 No.4
발행연도
2022.8
수록면
278 - 287 (10page)
DOI
10.4048/jbc.2022.25.e23

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Purpose: To determine whether smoking status (active/passive) affects recurrence events after breast cancer (BC) diagnosis among women. Methods: A comprehensive literature search of MEDLINE, Cochrane Central, EMBASE, and Web of Science databases on smoking status and BC outcomes retrieved 5,940 articles. After reviewing the inclusion and exclusion criteria, we selected 14 articles for a full review and synthesis. Results: Five studies were cohort retrospective, 6 were case-control, 2 were prospective cohort studies, and 1 was a secondary analysis of a randomized control trial. Among the 8 articles that focused on active smoking, 6 showed an increased risk of BC recurrence, and 2 showed no evidence of such an association. Studies that examined former smokers found little evidence of an increased risk of BC recurrence. This association may be dose-dependent. Conclusion: Given the current evidence, although limited, active smokers should quit smoking after BC diagnosis as trends indicate a positive association between active smoking and BC recurrence. More robust evidence is needed to assess such associations and examine the outcomes of quitting smoking in such patients.

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