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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.10
- 수록면
- 433 - 439 (7page)
이용수
초록· 키워드
오류제보하기
The rodent model has been used frequently to understand stroke pathophysiology, due to its low costand the large spectrum of genetic strains available. Here, we present a diffuse speckle contrast analysissystem (DSCA) with a 1 × 2 optical switch that was used to non-invasively assess cerebral blood flow(CBF) changes in the rat during intraluminal suturing for middle cerebral artery occlusion (MCAO) surgery.
The blood flow index (BFI) in the left hemisphere was lower than that in the right hemisphere becausethe left middle cerebral artery was occluded. Furthermore, the performance of the DSCA system wascompared with that of commercial laser Doppler flowmetry. The changes in the BFI measured by thetwo systems were correlated strongly. The DSCA system was less sensitive to motion artifacts and ableto measure relatively deep tissue flow in the rat’s brain. In conclusion, the DSCA system secured CBFmonitoring during surgery in a rodent model without craniotomy.
목차
등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
J. V. Gijn / 1998 / Issues and answers in stroke care / Lancet 352(Suppl. 3):SIII23~SIII27
G. Pignataro / 2009 / Post-ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy / FEBS J 276(1):46~57
T. Kirino / 2002 / Ischemic tolerance / J. Cereb. Blood Flow Metab 22(11):1283~1296
A. Durukan / 2008 / Rodent models of ischemic stroke : a useful tool for stroke drug development / Curr. Pharm. Des 14(4):359~370
H. Memezawa / 1992 / Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats / Stroke 23(4):552~559
G. Pignataro / 2009 / Post-ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy / FEBS J 276(1):46~57
T. Kirino / 2002 / Ischemic tolerance / J. Cereb. Blood Flow Metab 22(11):1283~1296
A. Durukan / 2008 / Rodent models of ischemic stroke : a useful tool for stroke drug development / Curr. Pharm. Des 14(4):359~370
H. Memezawa / 1992 / Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats / Stroke 23(4):552~559
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