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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.2
- 수록면
- 88 - 93 (6page)
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Recently laser speckle contrast (LSC) imaging has become a widely used optical method for in vivoassessment of blood flow in the animal brain. LSC imaging is useful for monitoring brain hemodynamicswith relatively high spatio-temporal resolution. A speckle contrast imaging system has been implementedwith electrical sensory stimulation apparatus. LSC imaging is combined with optical intrinsic signal imagingin order to measure changes in cerebral blood flow as well as neural activity in response to electricalsensory stimulation applied to the hindlimb region of the mouse brain. We found that blood flow andoxygen consumption are correlated and both sides of hindlimb activation regions are symmetrically located.
This apparatus could be used to monitor spatial or temporal responses of cerebral blood flow in animaldisease models such as ischemic stroke or cortical spreading depression.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
A. K. Dunn / 2001 / Dynamic imaging of cerebral blood flow using laser speckle / Journal of Cerebral Blood Flow & Metabolism 21:195~201
T. Durduran / 2004 / Spatiotemporal quantification of cerebral blood flow during functional activation in rat somatosensory cortex using laser-speckle flowmetry / Journal of Cerebral Blood Flow & Metabolism 24:518~525
N. Li / 2009 / High spatiotemporal resolution imaging of the neurovascular response to electrical stimulation of rat peripheral trigeminal nerve as revealed by in vivo temporal laser speckle contrast / Journal of Neuroscience Methods 176:230~236
B. Weber / 2004 / Optical imaging of the spatiotemporal dynamics of cerebral blood flow and oxidative metabolism in the rat barrel cortex / Eur. J. Neurosci 20:2664~2670
B. Weber / 2014 / Optical Imaging of Neocortical Dynamics / Springer
T. Durduran / 2004 / Spatiotemporal quantification of cerebral blood flow during functional activation in rat somatosensory cortex using laser-speckle flowmetry / Journal of Cerebral Blood Flow & Metabolism 24:518~525
N. Li / 2009 / High spatiotemporal resolution imaging of the neurovascular response to electrical stimulation of rat peripheral trigeminal nerve as revealed by in vivo temporal laser speckle contrast / Journal of Neuroscience Methods 176:230~236
B. Weber / 2004 / Optical imaging of the spatiotemporal dynamics of cerebral blood flow and oxidative metabolism in the rat barrel cortex / Eur. J. Neurosci 20:2664~2670
B. Weber / 2014 / Optical Imaging of Neocortical Dynamics / Springer
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