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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.6
- 수록면
- 148 - 153 (6page)
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The lignan compound of Schisandra chinensis Baill. (Schizandraceae) has been reported to have a variety of biological activities such as liver protection, neuroprotection, anti-oxidant and anti-diabetes. In this study, we investigated a quantitative analytical method for schisandrin, gomisin A and gomisin M₂ isolated from S. chinensis by high-performance liquid chromatography-ultraviolet spectroscopy (HPLC-UV). The isolated compounds were identified by the analysis of 1H- and 13CNMR spectroscopic data. The results showed that calibration curves of three compounds indicated great linearity with a correlation coefficient (R²) ) of schisandrin 0.9983, gomisin A 0.9982 and gomisin M₂ 0.9986. The limits of detection (LOD) of schisandrin, gomisin A and gomisin M₂ were 0.14, 0.07 and 0.05 μg/ml and the limits of quantification (LOQ) were 0.42, 0.22 and 0.14 μg/ml. Intra-day and inter-day precisions of schisandrin were 0.40~1.44%, 0.07~1.02% gomsin A were 0.22~0.52%, 0.10~0.63%, gomisin M2 were 0.40~0.99%, 0.81~2.88%. In result, contents of schisandrin, gomisin A and gomisin M₂ in ethanol extract of S. chinensis were 25.95±0.15, 2.51±0.02 and 2.17±0.07 mg/g.
목차
Abstract
재료 및 방법
결과 및 고찰
결론
인용문헌
참고문헌 (21)
참고문헌 신청
Jung, G. T. / 2000 / The antioxudative, antimicrobial and nitrite scavenging effects of schizandra chinensis ruprecht (Omija) seed / Korean J. Food Sci. Technol 32:928~935
목철균 / 2005 / 오미자추출액/포도과즙 혼합 즉성 추출차의 품질특성 / 산업식품공학 9(3):226~230
Ip, S. P. / 1998 / Structure-activity relationship of schisandrins in enhancing liver mitochondrial glutathione status in CCl4-poisoned mice / Acta Pharmacol. Sin 4:313~316
Sowndhararajan, K. / 2018 / An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis / Biomed. Pharmacother 97:958~968
Zhang, L. / 2013 / Antioxidant and anti-proliferative activities of five compounds from Schisandra chinensis fruit / Ind. Crops Prod 50:690~693
목철균 / 2005 / 오미자추출액/포도과즙 혼합 즉성 추출차의 품질특성 / 산업식품공학 9(3):226~230
Ip, S. P. / 1998 / Structure-activity relationship of schisandrins in enhancing liver mitochondrial glutathione status in CCl4-poisoned mice / Acta Pharmacol. Sin 4:313~316
Sowndhararajan, K. / 2018 / An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis / Biomed. Pharmacother 97:958~968
Zhang, L. / 2013 / Antioxidant and anti-proliferative activities of five compounds from Schisandra chinensis fruit / Ind. Crops Prod 50:690~693
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