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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.6
- 수록면
- 102 - 110 (9page)
- DOI
- 10.22889/KJP.2024.55.2.102
이용수
초록· 키워드
오류제보하기
Schisandra chinensis (S. chinensis) contains several compounds that exhibit various physiological activities such as anti-oxidation and anti-inflammation. The major compounds of S. chinensis are lignans such as schisandrol A, schisandrol B, schisandrin A, gomisin N and schisandrin C. In this study, the contents of five lignans from S. chinensis was quantitatively analyzed by using high-performance liquid chromatography (HPLC) to find the optimal extraction method. Additionally, the analysis method was validated and a simultaneous analysis method was established. DPPH and ABTS scavenging assays were performed to evaluate the anti-oxidant effect of S. chinensis extracts and fractions. The results showed that the calibration curves of five lignans exhibited high linearity with a correlation coefficient (R²) of 0.9998. The optimal extraction method for S. chinensis was the reflux extraction method with 60% ethanol at 100℃ and the contents of five lignans were 1.73, 0.28, 0.85, 1.28 and 0.41%. The contents of five lignans in n-hexane fraction was 6.1 to 8.5 times compared with those in the extract prepared by optimal extraction method. The results of anti-oxidation of S. chinensis extracts and fractions showed that the anti-oxidant effect was increased dose-dependently depending on the contents of five lignans. Therefore, these results could be used as basic data for the standardization of anti-oxidant health functional foods, cosmetics and medicines including five lignans, which are the active compounds of S. chinensis.
목차
Abstract
재료 및 방법
결과 및 고찰
결론
인용문헌
참고문헌 (22)
참고문헌 신청
Lee, J. H., Jeong, K. O., Im, S. Y., Jin, D. M., Lee, S. W. and Lim, J. M. (2022) Analysis of schizandrin content and biological activities of Schisandra chinensis extract. Kor. J. Pharmacogn. 53: 213-225.
Cho, H. E., Choi, Y. J. and Cho, E. K. (2010) Antioxidant and nitrite scavening activity and α-glucosidase inhibitory effect of water extract from Schizandra chinensis Baillon. J. Korean Soc. Food Sci. Nutr. 39: 481-486.
Jeon, Y. H., Kil, J. H., Lim, S. M., Kim, M. H. and Kim, M. R. (2008) Analysis of antioxidative activity and antimutagenic effect of ethanol extract from Schizandra chinensis Baillon. J. East Asian Soc. Dietary Life 18: 746-752.
Kim, M. J. and Park, E. J. (2010) Antioxidative and antigenotoxic effect of Omija (Schizandra chinensis B.) extracted with various solvents. J. Korean Soc. Food Sci. Nutr. 39: 487-493.
Kim, H. W., Shin, J. H., Lee, M. K., Jang, G. H., Lee, S. H., Jang, H. H., Jeong, S. T. and Kim, J. B. (2015) Qualitative and quantitative analysis of dibenzocyclooctadiene lignans for the fruits of Korean “Omija” (Schisandra chinensis). Korean J. Medicinal Crop Sci. 23: 385-394.
Cho, H. E., Choi, Y. J. and Cho, E. K. (2010) Antioxidant and nitrite scavening activity and α-glucosidase inhibitory effect of water extract from Schizandra chinensis Baillon. J. Korean Soc. Food Sci. Nutr. 39: 481-486.
Jeon, Y. H., Kil, J. H., Lim, S. M., Kim, M. H. and Kim, M. R. (2008) Analysis of antioxidative activity and antimutagenic effect of ethanol extract from Schizandra chinensis Baillon. J. East Asian Soc. Dietary Life 18: 746-752.
Kim, M. J. and Park, E. J. (2010) Antioxidative and antigenotoxic effect of Omija (Schizandra chinensis B.) extracted with various solvents. J. Korean Soc. Food Sci. Nutr. 39: 487-493.
Kim, H. W., Shin, J. H., Lee, M. K., Jang, G. H., Lee, S. H., Jang, H. H., Jeong, S. T. and Kim, J. B. (2015) Qualitative and quantitative analysis of dibenzocyclooctadiene lignans for the fruits of Korean “Omija” (Schisandra chinensis). Korean J. Medicinal Crop Sci. 23: 385-394.
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