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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.9
- 수록면
- 195 - 201 (7page)
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초록· 키워드
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To develop new therapy for prevention and treatment of hair loss is very important according to increase of the number of hair loss people. The aim of this study was to investigate the hair growth promoting effects of pectin lyase-modified red ginseng extract (GS-E3D). We examined antioxidant and anti-inflammatory effects, human hair dermal papilla cells (HHDPC) proliferation, and testoterone-induced 5α-reductase inhibitory effects. GS-E3D show not only 1,1-diphenyl-2-picryhydrazyl (DPPH) radical scavenging activity and xanthine oxidase inhibitory effects as an anti-oxidant property, but also lipoxygenase and hyaluronidase inhibitory effects as an anti-inflammatory property. Human hair dermal papilla cells proliferation by GS-E3D was higher than those of minoxidil or finasteride, using the positive controls. Moreover, GS-E3D exhibited 5α-reductase inhibitory activities after stimulating by testoterone. The present results indicate that GS-E3D has a potential to be as an hair growth promoting agent for cosmetic materials.
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참고문헌 (39)
참고문헌 신청
Rho, S. S. / 2005 / The hair growth promoting effect of Asiasari radix extract and its molecular regulation / J. Dermatol. Sci 38:89~97
김재환 / 2009 / 고려 홍삼의 탈모증 개선 효과에 대한 임상 연구 / Journal of Ginseng Research 33(3):223~228
Yun, T. K. / 2001 / Brief introduction of Panax ginseng C.A. Meyer / J. Korean Med. Sci 16(Suppl):S3~S5
임경택 / 2016 / Ginseng, the natural effectual antiviral: Protective effects of Korean Red Ginseng against viral infection / Journal of Ginseng Research 40(4):309~314
Lee, N. / 2016 / Antifatigue effects of enzyme-modified ginseng extract: a randomized, double-blind, placebo-controlled trial / J. Altern. Complement Med 22:859~864
김재환 / 2009 / 고려 홍삼의 탈모증 개선 효과에 대한 임상 연구 / Journal of Ginseng Research 33(3):223~228
Yun, T. K. / 2001 / Brief introduction of Panax ginseng C.A. Meyer / J. Korean Med. Sci 16(Suppl):S3~S5
임경택 / 2016 / Ginseng, the natural effectual antiviral: Protective effects of Korean Red Ginseng against viral infection / Journal of Ginseng Research 40(4):309~314
Lee, N. / 2016 / Antifatigue effects of enzyme-modified ginseng extract: a randomized, double-blind, placebo-controlled trial / J. Altern. Complement Med 22:859~864
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