지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.4
- 수록면
- 103 - 108 (6page)
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초록· 키워드
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The purpose of this study was to determine the hair growth effects of lavender oil (LO) in female C57BL/6 mice. The experimental animals were divided into a normal group (N: saline), a vehicle control group(VC: jojoba oil), a positive control group (PC: 3% minoxidil), experimental group 1 (E1: 3% LO), and experimental group 2 (E2: 5% LO). Test compound solutions were topically applied to the backs of the mice (100 μL per application), once per day, 5 times a week, for 4 weeks. The changes in hair follicle number, dermal thickness, and hair follicle depth were observed in skin tissues stained with hematoxylin and eosin, and the number of mast cells was measured in the dermal and hypodermal layers stained with toluidine blue. PC, E1, and E2 groups showed a significantly increased number of hair follicles, deepened hair follicle depth, and thickened dermal layer, along with a significantly decreased number of mast cells compared to the N group. These results indicated that LO has a marked hair growth-promoting effect, as observed morphologically and histologically. There was no significant difference in the weight of the thymus among the groups. However, both absolute and relative weights of the spleen were significantly higher in the PC group than in the N, VC, E1, or E2 group at week 4. Thus, LO could be practically applied as a hair growth-promoting agent.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (16)
참고문헌 신청
Hadshiew, I.M., Foitzik, K., Arck, P.C. and Paus, R. (2004) Burden of hair loss: stress and the underestimated psychosocial impact of telogen effluvium and androgenetic alopecia. J. Invest. Dermatol., 123, 455-457
Rho, S.S., Park, S.J., Hwang, S.L., Lee, M.H., Kim, C.D., Lee, I.H., Chang, S.Y. and Rang, M.J. (2005) The hair growth promoting effect of Asiasari radix extract and its molecular regulation. J. Dermatol. Sci., 38, 89-97
Cash, T.F., Price, V.H. and Savin, R.C. (1993) Psychological effects of androgenetic alopecia on women: comparisons with balding men and with female control subjects. J. Am. Acad. Dematol., 29, 568-575
Alonso, L. and Fuchs, E. (2006) The hair cycle. J. Cell Sci., 119, 391-393
Paus, R., Christoph, T. and Müller-Röver, S. (1999) Immunology of the hair follicle: a short journey into terra incognita. J. Investig. Dermatol. Symp. Proc., 4, 226-234
Rho, S.S., Park, S.J., Hwang, S.L., Lee, M.H., Kim, C.D., Lee, I.H., Chang, S.Y. and Rang, M.J. (2005) The hair growth promoting effect of Asiasari radix extract and its molecular regulation. J. Dermatol. Sci., 38, 89-97
Cash, T.F., Price, V.H. and Savin, R.C. (1993) Psychological effects of androgenetic alopecia on women: comparisons with balding men and with female control subjects. J. Am. Acad. Dematol., 29, 568-575
Alonso, L. and Fuchs, E. (2006) The hair cycle. J. Cell Sci., 119, 391-393
Paus, R., Christoph, T. and Müller-Röver, S. (1999) Immunology of the hair follicle: a short journey into terra incognita. J. Investig. Dermatol. Symp. Proc., 4, 226-234
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UCI(KEPA) : I410-ECN-0101-2016-513-002786553