지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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The drug inducing tubulointerstitial nephritis is a crucial cause of acute kidney injury. Use of herbal plants in disease treatment is generally practiced in Korea. Although there are a small number of case reports, tubulointerstitial nephritis caused by taking Atractylodes macrocephala Koidzumi in human has never been reported. A 62-year-old man visited our hospital with symptoms of systemic edema accompanied by reduced urine volume and dyspnea after taking herbal plant 1 week ago. Chest radiographs showed both sided pleural effusion. Blood test results showed elevation of serum blood urea nitrogen and creatinine level and urine test results showed hematuria and proteinuria. Renal biopsy result showed evidence of tubulointerstitial nephritis by tubulitis and inflammatory cell expansion in the interstitium was observed. The patient’s renal function recovered after administration of active renal replacement treatment and conservative therapy such as supplementation of fluid and electrolytes, and there was no disease recurrence for 1 year. Therefore, this case proved that Atractylodes macrocephala Koidzumi could cause acute kidney injury by the drug induced tubulointerstitial nephritis in human.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Weici T / 1992 / Atractylodes macrocephala Koidz. Chinese Drugs of Plant Origin / Springer Berlin Heidelberg :199~201
Lee YP / 2012 / Effect of Atractylodes macrocephala on Hypertonic Stress-Induced Water Channel Protein Expression in Renal Collecting Duct Cells / Evid Based Complement Alternat Med 2012:650809
Hodgkins KS / 2012 / Tubulointerstitial injury and the progression of chronic kidney disease / Pediatr Nephrol 27:901~909
Buysen JG / 1990 / Acute interstitial nephritis a clinical and morphological study in 27 patients / Nephrol Dial Transplant 5:94~99
Peres LA / 2013 / Acute nephrotoxicity of cisplatin:molecular mechanisms / J Bras Nefrol 35:332~340
Lee YP / 2012 / Effect of Atractylodes macrocephala on Hypertonic Stress-Induced Water Channel Protein Expression in Renal Collecting Duct Cells / Evid Based Complement Alternat Med 2012:650809
Hodgkins KS / 2012 / Tubulointerstitial injury and the progression of chronic kidney disease / Pediatr Nephrol 27:901~909
Buysen JG / 1990 / Acute interstitial nephritis a clinical and morphological study in 27 patients / Nephrol Dial Transplant 5:94~99
Peres LA / 2013 / Acute nephrotoxicity of cisplatin:molecular mechanisms / J Bras Nefrol 35:332~340
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