지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.6
- 수록면
- 59 - 63 (5page)
- DOI
- http://dx.doi.org/10.12701/yujm.2016.33.1.59
이용수
초록· 키워드
오류제보하기
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and severe drug-induced hypersensitivity syndrome characterized by hematological abnormalities and multiorgan involvement.
Liver involvement is the most common visceral manifestation. However, renal failure has been rarely described.
The common culprit drugs are anticonvulsants and allopurinol. We experienced a patient with DRESS syndrome with acute interstitial nephritis caused by concomitant administration of quinolone and non-steroidal anti-inflammatory drugs (NSAIDs). A 41-year-old man presented with a diffuse erythematous rash and fever which developed after administration of quinolone and NSAIDs for a month due to prostatitis. He was diagnosed with DRESS syndrome. Skin rash, fever, eosinophilia, and elevations of liver enzymes improved with conservative treatment and discontinuation of the causative drugs. However, deterioration of his renal function occurred on day 8 of admission. The levels of blood urea nitrogen and serum creatinine increased and oliguria, proteinuria and urinary eosinophils were observed. Ultrasonography showed diffuse renal enlargement. The clinical features were compatible with acute interstitial nephritis. Despite intravenous rehydration and diuretics, renal function did not improve. After hemodialysis, his renal function recovered completely within 2 weeks without administration of systemic corticosteroid.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Criado PR / 2012 / Drug reaction with eosinophilia and systemic symptoms (DRESS)/druginduced hypersensitivity syndrome (DIHS): a review of current concepts / An Bras Dermatol 87:435~449
Cacoub P / 2011 / The DRESS syndrome: a literature review / Am J Med 124:588~597
Augusto JF / 2009 / A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis / Nephrol Dial Transplant 24:2940~2942
Díaz-Mancebo R / 2012 / Dress syndrome and acute tubulointerstitial nephritis after treatment with vancomycin and beta-lactams. Case report and literature review / Nefrologia 32:685~687
O’Meara P / 2011 / DRESS with delayed onset acute interstitial nephritis and profound refractory eosinophilia secondary to Vancomycin / Allergy Asthma Clin Immunol 7:16
Cacoub P / 2011 / The DRESS syndrome: a literature review / Am J Med 124:588~597
Augusto JF / 2009 / A case of sulphasalazine-induced DRESS syndrome with delayed acute interstitial nephritis / Nephrol Dial Transplant 24:2940~2942
Díaz-Mancebo R / 2012 / Dress syndrome and acute tubulointerstitial nephritis after treatment with vancomycin and beta-lactams. Case report and literature review / Nefrologia 32:685~687
O’Meara P / 2011 / DRESS with delayed onset acute interstitial nephritis and profound refractory eosinophilia secondary to Vancomycin / Allergy Asthma Clin Immunol 7:16
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