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A comparison of postoperative emergence agitation between sevoflurane and thiopental anesthesia induction in pediatric patients
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논문 기본 정보

Type
Academic journal
Author
고성훈 (전북대학교)
Journal
대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.68 No.4 KCI Accredited Journals
Published
2015.1
Pages
373 - 378 (6page)

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A comparison of postoperative emergence agitation between sevoflurane and thiopental anesthesia induction in pediatric patients
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Background: This study was performed to compare the incidence of emergence agitation (EA) between inhalation and intravenous anesthesia induction in children after sevoflurane anesthesia. Methods: In this prospective and double-blind study, 100 children aged 3 to 7 years were enrolled. Subjects were randomly assigned to the sevoflurane (Group S) or thiopental (Group T) anesthesia induction groups. Anesthesia was induced using 8% sevoflurane and 4–6 mg/kg thiopental in Groups S and T, respectively. Anesthesia was maintained with nitrous oxide and sevoflurane. The children were evaluated at 5 and 20 min after arrival in the postanesthesia care unit (PACU) with a four-point agitation scale and the Pediatric Anesthesia Emergence Delirium scale. The incidence of EA and administration of the rescue agent were recorded. Results: The incidence of EA was significantly lower in Group T compared to Group S at 5 min after PACU arrival (3/49 patients, 6% vs. 12/47 patients, 26%, P = 0.019). However, there was no difference between the two groups at 20 min after PACU arrival (23/49 vs. 19/47 patients in Group T vs. Group S, P = 0.425). The overall incidence of EA was 60% (28/47 patients) in Group S and 41% (20/49 patients) in Group T (P = 0.102). The number of children who received propofol as a rescue agent was significantly lower in Group T (Group S: 14/47 vs. Group T: 5/49, P = 0.031). Conclusions: Intravenous anesthesia induction with thiopental reduced the incidence of EA in the early PACU period compared to inhalation induction with sevoflurane in 3- to 7-year-old children undergoing sevoflurane anesthesia.

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References (29)

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Sikich N / 2004 / Development and psychometric evaluation of the pediatric anesthesia emergence delirium scale / Anesthesiology 100:1138~1145 google schola Voepel-Lewis T / 2003 / A prospective cohort study of emergence agitation in the pediatric postanesthesia care unit / Anesth Analg 96:1625~1630 google schola Uezono S / 2000 / Emergence agitation after sevoflurane versus propofol in pediatric patients / Anesth Analg 91:563~566 google schola Welborn LG / 1996 / Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric ambulatory patients / Anesth Analg 83:917~920 google schola Cravero J / 2000 / Emergence agitation in paediatric patients after sevoflurane anaesthesia and no surgery : a comparison with halothane / Paediatr Anaesth 10:419~424 google schola

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