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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1,483 - 1,489 (7page)
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The prognostic impact of body mass index (BMI) in patients with upper tract urothelial carcinoma (UTUC) is an ongoing debate. Our study aimed to investigate the prognostic role of BMI in patients treated with radical nephroureterectomy (RNU) for UTUC from a multiinstitutional Korean collaboration. We retrospectively reviewed data from 440 patients who underwent RNU for UTUC at four institutions in Korea. To avoid biasing the survival estimates, patients who had previous or concomitant muscle-invasive bladder tumors were excluded. BMI was categorized into approximate quartiles with the lowest quartile assigned to the reference group. Kaplan-Meier and multivariate Cox regression analyses were performed to assess the influence of BMI on survival. The lower quartile BMI group showed significantly increased overall mortality (OM) and cancer specific mortality (CSM) compared to the 25%-50% quartiles and upper quartile BMI groups. Kaplan-Meier estimates showed similar results. Based on multivariate Cox regression analysis, preoperative BMI as a continuous variable was an independent predictor for OM and CSM. In conclusion, preoperative underweight patients with UTUC in Korea survive less after RNU. Preoperative BMI may provide additional prognostic information to establish risk factors.
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참고문헌 (30)
참고문헌 신청
Ehdaie B / 2014 / Postoperative nomogram for disease recurrence and cancer-specific death for upper tract urothelial carcinoma : comparison to American Joint Committee on Cancer Staging Classification / Urol J 11:1435~1441
Tawfiek ER / 1997 / Upper-tract transitional cell carcinoma / Urology 50:321~329
Margulis V / 2009 / Outcomes of radical nephroureterectomy : a series from the Upper Tract Urothelial Carcinoma Collaboration / Cancer 115:1224~1233
조양현 / 2014 / Predictors of Intravesical Recurrence After Radical Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma: An Inflammation-Based Prognostic Score / Investigative and Clinical Urology 55(7):453~459
Rouprêt M / 2013 / European guidelines on upper tract urothelial carcinomas : 2013 update / Eur Urol 63:1059~1071
Tawfiek ER / 1997 / Upper-tract transitional cell carcinoma / Urology 50:321~329
Margulis V / 2009 / Outcomes of radical nephroureterectomy : a series from the Upper Tract Urothelial Carcinoma Collaboration / Cancer 115:1224~1233
조양현 / 2014 / Predictors of Intravesical Recurrence After Radical Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma: An Inflammation-Based Prognostic Score / Investigative and Clinical Urology 55(7):453~459
Rouprêt M / 2013 / European guidelines on upper tract urothelial carcinomas : 2013 update / Eur Urol 63:1059~1071
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