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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 질병관리본부 Osong Public Health and Research Persptectives Osong Public Health and Research Persptectives Vol.8 No.1
- 발행연도
- 2017.1
- 수록면
- 3 - 10 (8page)
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초록· 키워드
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Objectives: Tuberculin skin reaction size is one indicator of bacillus Calmette-Guérin (BCG) vaccine efficacy and a way to diagnose latent infection. Several primary studies have examined this issue. Combining the results of these studies using a meta-analysis will provide reliable evidence regarding this indicator for policymakers. This study aimed to estimate the total frequency of different tuberculin skin test reactions among Iranian children and teenagers who received the BCG vaccination at birth. Methods: National and international databanks were searched using relevant keywords. After the search strategy was restricted and duplicates were excluded, the titles and abstracts of the remaining papers were screened. All included studies included healthy children who received the BCG vaccine without confirmed tuberculosis exposure. Heterogeneity of the results was assessed using the Cochrane test and I2 index showed the random effects model as the best model for estimating the pooled results. Results: We combined the results of 14 primary studies including purified protein derivative reaction test measures of 26,281 Iranian children. The frequencies (95% confidence intervals) of the reactions were 8.5% (6.2–10.8) for patients with a reaction size ≥ 10 mm, 29.9% (22.3–37.4) for a reaction size of 5–9 mm, and 60% (48.9–71.1) for a reaction size < 5 mm. Conclusion: Our study showed that large numbers of Iranian children and teens have no positive BCG vaccine reaction and a considerable number of children have been exposed to Mycobacterium tuberculosis.
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참고문헌 (32)
참고문헌 신청
Shirin Sayyahfar / 2014 / Comparison of Tuberculin Skin Test result and interferon gamma response to human PPD in BCG scar positive and negative children / Journal of Epidemiology and Global Health 4(1):45~50
Moosazadeh M / 2015 / Predicting the incidence of smear positive tuberculosis cases in Iran using time series analysis / Iran J Public Health 44:1526~1534
Mahmood Moosazadeh / 2015 / The incidence of recurrence of tuberculosis and its related factors in smear-positive pulmonary tuberculosis patients in Iran: A retrospective cohort study / Lung India 32(6):557
Moosazadeh M / 2015 / Predictive factors of death in patients with tuberculosis : a nested case-control study / East Mediterr Health J 21:287~292
Nasehi MM / 2012 / The epidemiology of factors associated with screening and treatment outcomes of patients with smear positive pulmonary tuberculosis : a populationbased study / J Mazand Univ Med Sci 21:9~18
Moosazadeh M / 2015 / Predicting the incidence of smear positive tuberculosis cases in Iran using time series analysis / Iran J Public Health 44:1526~1534
Mahmood Moosazadeh / 2015 / The incidence of recurrence of tuberculosis and its related factors in smear-positive pulmonary tuberculosis patients in Iran: A retrospective cohort study / Lung India 32(6):557
Moosazadeh M / 2015 / Predictive factors of death in patients with tuberculosis : a nested case-control study / East Mediterr Health J 21:287~292
Nasehi MM / 2012 / The epidemiology of factors associated with screening and treatment outcomes of patients with smear positive pulmonary tuberculosis : a populationbased study / J Mazand Univ Med Sci 21:9~18
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