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논문 기본 정보

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학술저널
저자정보
Lee Yun Woo (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul) Lim So Yun (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul) Lee Ji-Hyang (Department of Allergy and Clinical Immunology Asan Medical Center University of Ulsan College of Me) Lim Joon Seo (Clinical Research Center Asan Institute for Life Sciences Asan Medical Center University of Ulsan C) Kim Miseo (Office for Infection Control Asan Medical Center University of Ulsan College of Medicine Seoul Kore) Kwon Seonhee (Office for Infection Control Asan Medical Center University of Ulsan College of Medicine Seoul Kore) Joo Jiyeon (Office for Infection Control Asan Medical Center University of Ulsan College of Medicine Seoul Kore) Kwak Sun Hee (Office for Infection Control Asan Medical Center University of Ulsan College of Medicine Seoul Kore) Kim Eun Ok (Office for Infection Control Asan Medical Center University of Ulsan College of Medicine Seoul Kore) Jung Jiwon (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul) Kwon Hyouk-Soo (Department of Allergy and Clinical Immunology Asan Medical Center University of Ulsan College of Me) Kim Tae-Bum (Department of Allergy and Clinical Immunology Asan Medical Center University of Ulsan College of Me) Kim Sung-Han (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul) Bae Seongman (Department of Infectious Diseases Asan Medical Center University of Ulsan College of Medicine Seoul)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.21
발행연도
2021.1
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1 - 6 (6page)

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초록· 키워드

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We conducted a prospective, mobile-based survey on the self-reported adverse reactions in healthcare workers (HCWs) who received both doses of the BNT162b2 mRNA vaccine. Of the 342 HCWs who completed the two-dose vaccination, 265 (77.5%) responded to the survey at least once. Overall, the rates of adverse reactions were higher after the second dose compared with the first dose (89.1% vs. 80.1%, P = 0.006). The most common systemic reactions were muscle ache (69.1%), fatigue (65.7%), headache (48.7%), chills (44.2%), and fever (32.1%), and were notably more common after the second dose vaccine as well. We also noted a sex difference in which the frequency of adverse reactions after the second dose of the vaccine was significantly higher in females, which was not observed after the first dose. The rates of adverse reactions were lower in older age groups, and the rates and severities of the adverse reactions decreased during the 3-day period following vaccination.
#COVID-19 #Vaccination #Adverse Reaction #BNT162b2

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참고문헌 (7)

참고문헌 신청
Johanna Chapin-Bardales / 2021 / Reactogenicity Following Receipt of mRNA-Based COVID-19 Vaccines / JAMA 325(21):2201 Crossref Polack FP / 2020 / Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine / N Engl J Med 383(27):2603~2615 google schola Walsh EE / 2020 / Safety and immunogenicity of two RNA-based Covid-19 vaccine candidates / N Engl J Med 383(25):2439~2450 google schola Bae Seongman / 2021 / Adverse Reactions Following the First Dose of ChAdOx1 nCoV-19 Vaccine and BNT162b2 Vaccine for Healthcare Workers in South Korea / Journal of Korean Medical Science 36(17):1~9 dbpia Cristina Menni / 2021 / Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study / The Lancet Infectious Diseases 21(7):939~949 Crossref

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