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논문 기본 정보

자료유형
학술저널
저자정보
Elham Aboualigalehdari (Ilam University of Medical Sciences) Nourkhoda Sadeghifard (Ilam University of Medical Sciences) Morovat Taherikalani (Lorestan University of Medical Sciences) Zaynab Zargoush (Ilam University of Medical Sciences) Zahra Tahmasebi (Ilam University of Medical Sciences) Behzad Badakhsh (Ilam University of Medical Sciences) Arman Rostamzad (Ilam University of Medical Sciences) Sobhan Ghafourian (Ilam University of Medical Sciences) Iraj Pakzad (Ilam University of Medical Sciences)
저널정보
질병관리본부 Osong Public Health and Research Persptectives Osong Public Health and Research Persptectives Vol.7 No.2
발행연도
2016.1
수록면
116 - 118 (3page)

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Objectives: Vaginitis still remains as a health issue in women. It is notable that Candida albicans producing biofilm is considered a microorganism responsible for vaginitis with hard to treat. Also, Peganum harmala was applied as an anti fungal in treatment for many infections in Iran. Therefore, this study goal to investigate the role of P. harmala in inhibition of biofilm formation in C. albicans. Methods: So, 27 C. albicans collected from women with Vaginitis, then subjected for biofilm formation assay. P. harmala was applied as antibiofilm formation in C. albicans. Results: Our results demonstrated that P. harmala in concentration of 12 ㎍/ml easily inhibited strong biofilm formation; while the concentrations of 10 and 6 ㎍/ml inhibited biofilm formation in moderate and weak biofilm formation C. albicans strains, respectively. Conclusion: Hence, the current study presented P. harmala as antibiofilm herbal medicine for C. albicans; but in vivo study suggested to be performed to confirm its effectiveness.

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