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논문 기본 정보

자료유형
학술저널
저자정보
Si Young Lee (Professor Department of Microbiology and Immunology College of Dentistry Gangneung-Wonju National U) Hye Young Yoon (Ph.D. Student Department of Microbiology and Immunology College of Dentistry Gangneung-Wonju Nation)
저널정보
조선대학교 치의학연구원 Oral Biology Research Oral Biology Research 제46권 제3호
발행연도
2022.9
수록면
106 - 110 (5page)
DOI
10.21851/obr.46.03.202209.106

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Various disinfectants are used to remove biofilms formed in dental unit waterlines (DUWLs). This study aimed to assess the antibiofilm effects of cetylpyridinium chloride (CPC) on DUWL biofilms formed in a CDC Biofilm Reactor model and evaluate the feasibility of CPC as a novel DUWL disinfectant. For experiments, CPC was used at concentrations of 0.003125% to 0.00039%. Well-established DUWL disinfectants, such as 0.5% sodium hypochlorite (NaOCl), 0.12% chlorhexidine (CHX), and a mixture of 0.12% CHX and 12% ethanol, were used as standards. DUWL biofilms formed in the CDC Biofilm Reactor model were exposed to the disinfecting agents for 15 min. The number of living bacteria in the biofilms before and after exposure to chemicals were compared, and the biofilm reduction rate was calculated. The biofilm reduction rate of CPC at a concentration higher than 0.001562% was greater than that of all other conventional disinfecting agents. These findings suggest that CPC can be used for effective removal of DUWL biofilms. Key Words:

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