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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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The Endeavor ResoluteⓇ (ER) is a zotarolimus-eluting stent (ZES) with a biocompatibleBioLinx polymer. This study prospectively compared the clinical outcomes of 2 versionsof ZES, ER and Endeavor SprintⓇ (ES), in patients with multivessel disease. A totalof 488 patients who underwent multivessel percutaneous coronary intervention (PCI)were divided into 2 groups the ER group (n=288) and the ES group (n=200). The primaryendpoint was a composite of major adverse cardiac events (MACE) consisting of death,myocardial infarction, and target vessel revascularization after 12 months. In all patients,the prevalence of diabetes was higher in the ER group (42.7% vs. 31.0%, p=0.009). The rate of post-PCI Thrombolysis in Myocardial Infarction flow grade 3 was higherin the ER group (100.0% vs. 98.0%, p=0.028). There were no between-group differencesin the in-hospital, 1-month and 12-month clinical outcomes. In the propensity scorematched cohort (n=200 in each group), no differences were observed in the baseline andprocedural characteristics. There were no statistical differences in the rates of in-hospital,1-month and 12-month events (12-month MACE in the ER and ES groups: 6.0%vs. 3.5%, p=0.240, respectively). The safety and efficacy of both versions of ZES werecomparable in patients with multivessel disease during a 12-month clinical follow-up.
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참고문헌 (25)
참고문헌 신청
Kandzari DE / 2006 / Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent / J Interv Cardiol 19:405~413
Meredith IT / 2009 / Clinical and angiographic results with the next-generation resolute stent system: a prospective, multicenter, first-in-human trial / JACC Cardiovasc Interv 2:977~985
Williams PD / 2017 / Stent selection for percutaneous coronary intervention / Cont Cardiol Educ 3:64~69
Price MJ / 2017 / Safety and efficacy of the next generation Resolute Onyx zotarolimus-eluting stent: primary outcome of the RESOLUTE ONYX core trial / Catheter Cardiovasc Interv
Kandzari DE / 2006 / Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial / J Am Coll Cardiol 48:2440~2447
Meredith IT / 2009 / Clinical and angiographic results with the next-generation resolute stent system: a prospective, multicenter, first-in-human trial / JACC Cardiovasc Interv 2:977~985
Williams PD / 2017 / Stent selection for percutaneous coronary intervention / Cont Cardiol Educ 3:64~69
Price MJ / 2017 / Safety and efficacy of the next generation Resolute Onyx zotarolimus-eluting stent: primary outcome of the RESOLUTE ONYX core trial / Catheter Cardiovasc Interv
Kandzari DE / 2006 / Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial / J Am Coll Cardiol 48:2440~2447
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Optical Coherence Tomography-Guided Percutaneous Intervention: A Comparative Study
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