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자료유형
학술저널
저자정보
Xiaofan Yu (Department of Cardiology General Hospital of Shenyang Military Region Shenyang Liao Ning) Yi Li (Department of Cardiology General Hospital of Shenyang Military Region Shenyang Liao Ning) Qiancheng Wang (Department of Cardiology The Second Hospital of Dalian Medical University Dalian Liao Ning) Ming Liang (Department of Cardiology General Hospital of Shenyang Military Region Shenyang Liao Ning) Kai Xu (Department of Cardiology General Hospital of Shenyang Military Region Shenyang Liao Ning) Yaling Han (Department of Cardiology General Hospital of Shenyang Military Region Shenyang Liao Ning)
저널정보
대한심장학회 Korean Circulation Journal Korean Circulation Journal Vol.46 No.6
발행연도
2016.1
수록면
774 - 783 (10page)

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Background and Objectives: To compare clinical outcomes of staged versus “one-time” percutaneous coronary intervention (PCI) in intermediate to very high-risk patients with non–ST-segment elevation acute coronary syndromes (NSTE-ACS) and multivessel coronary disease (MVD). Subjects and Methods: 1531 NSTE-ACS patients with multivessel PCI and meeting the criteria of intermediate to very high risk were screened from a prospectively registered database obtained from General Hospital of Shenyang Military Region between 2008 and 2012. They were categorized into “one-time” PCI (n=859) and staged PCI (n=672) according to intervention strategy. The primary outcomes included a 3-year major adverse cardiac event (MACE), a composite of cardiac death, myocardial infarction (MI), and target vessel revascularization. Results: At 3 years, no significant differences in MACE (20.8% vs. 19.7%, p=0.608) and cardiac death/MI (7.1% vs. 9.1%, p=0.129) were observed between the two groups. After propensity score matching, there was no statistical significance in MACE (18.9% vs. 21.8%, p=0.249); whereas cardiac death/MI was significantly lower in the staged PCI group (7.0% vs.11.1%, p=0.033). Ninety-day landmark analysis showed that the staged PCI group had a lower 90-day incidence of MACE (1.2% vs. 3.3%, p= 0.037) and cardiac death/MI (0.7% vs. 2.6%, p=0.031). For the 90-day to 3-year follow-up period, the incidences of MACE (17.9% vs. 19.1%, p=0.641) and cardiac death/MI (6.3% vs. 8.7%, p=0.191) were similar in both groups. Conclusion: In intermediate- to very high-risk NSTE-ACS patients with MVD, staged PCI is superior to “one-time” PCI in terms of cardiac death/MI.

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