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논문 기본 정보

자료유형
학술저널
저자정보
Ken Kinjo (Fukuoka University Chikushi Hospital) Toshiyuki Matsui (Fukuoka University Chikushi Hospital) Takashi Hisabe (Fukuoka University Chikushi Hospital) Hiroshi Ishihara (Fukuoka University Chikushi Hospital) Toshiki Kojima (Fukuoka University Chikushi Hospital) Kenta Chuman (Fukuoka University Chikushi Hospital) Shigeyoshi Yasukawa (Fukuoka University Chikushi Hospital) Tsuyoshi Beppu (Fukuoka University Chikushi Hospital) Akihiro Koga (Fukuoka University Chikushi Hospital) Satoshi Ishikawa (Fukuoka University Chikushi Hospital) Masahiro Kishi (Fukuoka University Chikushi Hospital) Noritaka Takatsu (Fukuoka University Chikushi Hospital) Fumihito Hirai (Fukuoka University Chikushi Hospital) Kenshi Yao (Fukuoka University Chikushi Hospital) Toshiharu Ueki (Fukuoka University Chikushi Hospital) Masakazu Washio (St. Mary’s College)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.16 No.3
발행연도
2018.1
수록면
458 - 466 (9page)

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Background/Aims: Colonic diverticular hemorrhage (DH) was a rare disease until the 1990s, and its incidence has increased rapidly since 2000 in Japan. In recent years, colonic DH has been the most frequent cause of lower gastrointestinal bleeding (LGIB). Nearly all cases of DH are mild, with the bleeding often stopping spontaneously. Some cases, however, require surgery or arterial embolization. In this study, using a cohort at Fukuoka University Chikushi Hospital, we investigated factors associated with severe colonic DH. Methods: Among patients with LGIB who underwent colonoscopy at our hospital between 1995 and 2013, DH was identified in 273 patients. Among them, 62 patients (22.7%) were defined as having severe colonic DH according to recurrence of bleeding in a short period, and/or the necessity of transfusion, arterial embolization, or surgery. We then evaluated risk factors for severe DH among DH patients in this retrospective cohort. Results: Among the 273 patients with DH, use of non-steroidal anti-inflammatory drugs (NSAIDs) (odds ratio [OR], 2.801; 95% confidence interval [CI], 1.164–6.742), Charlson Risk Index (CRI) ≥2 (OR, 3.336; 95% CI, 1.154–7.353), right-sided colonic DH (OR, 3.873; 95% CI, 1.554–9.653), and symptoms of cerebral hypoperfusion (such as light-headedness, dizziness, or syncope) (OR, 2.926; 95% CI, 1.310–6.535) showed an increased risk of severe DH even after controlling for other factors. Conclusions: Severe DH occurred in 23% of DH patients, and NSAID use, CRI ≥2, right-sided colonic DH, and symptoms of cerebral hypoperfusion are suggested to be predictors of severe DH.

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