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논문 기본 정보

자료유형
학술저널
저자정보
Kyeong Min Kim (Department of Internal Medicine Eulji University College of Medicine Daejeon Korea) Soon Kil Kwon (Department of Internal Medicine Chungbuk National University College of Medicine Cheongju Korea) Hye-Young Kim (Department of Internal Medicine Chungbuk National University College of Medicine Cheongju Korea)
저널정보
전해질고혈압연구회 Electrolytes & Blood Pressure Electrolytes & Blood Pressure Vol.14 No.2
발행연도
2016.1
수록면
35 - 37 (3page)

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Familial renal glycosuria(FRG) is an inherited disorder characterized by persistent glycosuria in the absence of hyperglycemia. It is caused by mutations in the sodium-glucose co-transporter, leading to increase in the renal excretion of glucose and sodium. However, there have been no studies on the role of fasting and postprandial changes in the urinary sodium excretion in patients with FRG. We report a case of renal glycosuria, which was confirmed by a SLC5A2 mutation via gene sequencing, and compared the postprandial urinary glucose and sodium excretion. A 26-year-old man sometimes experienced glycosuria on routine screening; however, other laboratory findings were normal. His fasting and postprandial urinary glucose excretion levels were 295mg/dL and 2,170mg/dL, respectively. The fasting and postprandial urinary sodium excretion levels were 200mEq/L and 89mEq/L, respectively. In patients with FRG, excessive diuresis might be prevented by a compensatory mechanism that reduces postprandial sodium excretion.

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