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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국낙농식품응용생물학회 Journal of Dairy Science and Biotechnology Journal of Milk Science and Biotechnology Vol.36 No.3
- 발행연도
- 2018.1
- 수록면
- 164 - 170 (7page)
이용수
초록· 키워드
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The objectives of this study were to manufacture casein phosphopeptide (CPP)/chitosan oligosaccharide (CSO) nanocomplexes and to investigate the impacts of manufacturing variables, such as CPP concentration and pH, on their morphological and physicochemical characteristics. Transmission electron microscopy (TEM) and particle size analysis were used to assess the morphological and physicochemical properties of the CPP/CSO nanocomplexes, respectively. Based on the images obtained by TEM, the spherical shapes of the CPP/CSO nanocomplexes ranged from 50 to 150 nm. As the concentration of CPP was increased and the pH was decreased, the average particle size of the nanocomplexes significantly (p<0.05) increased. The CPP/CSO nanocomplexes had a highly uniform distribution with a polydispersity index value of less than 0.3. In addition, they had a negative surface charge with a zeta-potential value between —17 and —26 mV. The CPP/CSO nanocomplexes showed good stability during the freeze-drying process. In conclusion, CPP/CSO nanocomplexes were successfully manufactured, and the CPP concentration and pH were found to be key factors that affected their morphological and physicochemical properties.
목차
등록된 정보가 없습니다.
참고문헌 (12)
참고문헌 신청
Bharathiraja, S. / 2018 / Multimodal tumor-homing chitosan oligosaccharide-coated biocompatible palladium nanoparticles for photo-based imaging and therapy / Sci. Rep. 8:500
Bhattarai, N. / 2010 / Chitosan-based hydrogels for controlled, localized drug delivery / Adv. Drug Deliv. Rev. 62:83~99
Cao, Y. / 2017 / Bioactive peptides isolated from casein phosphopeptides enhance calcium and magnesium uptake in caco-2 cell monolayers / J. Agric. Food Chem. 65:2307~2314
Cilla, A. / 2011 / Effect of processing and food matrix on calcium and phosphorous bioavailability from milk-based beverages in caco-2 cells / Food Res. Int. 44:3030~3038
Ferraretto, A. / 2001 / Casein phosphopeptides influence calcium uptake by cultured human intestinal ht-29 tumor cells / J. Nutr. 131:1655~1661
Bhattarai, N. / 2010 / Chitosan-based hydrogels for controlled, localized drug delivery / Adv. Drug Deliv. Rev. 62:83~99
Cao, Y. / 2017 / Bioactive peptides isolated from casein phosphopeptides enhance calcium and magnesium uptake in caco-2 cell monolayers / J. Agric. Food Chem. 65:2307~2314
Cilla, A. / 2011 / Effect of processing and food matrix on calcium and phosphorous bioavailability from milk-based beverages in caco-2 cells / Food Res. Int. 44:3030~3038
Ferraretto, A. / 2001 / Casein phosphopeptides influence calcium uptake by cultured human intestinal ht-29 tumor cells / J. Nutr. 131:1655~1661
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