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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 243 - 253 (11page)
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초록· 키워드
오류제보하기
Brentuximab vedotin (BV), a potent antibody-drug conjugate, targets the CD30 antigen. Owing to the remarkable efficacy shown in CD30-positive lymphomas, such as Hodgkin’s lymphoma and systemic anaplastic large-cell lymphoma, BV was granted ac-celerated approval in 2011 by the US Food and Drug Administration. Thereafter, many large-scale trials in various situations have been performed, which led to extensions of the original indication. The aim of this review was to describe the latest updates on clinical trials of BV and the in-practice guidance for the use of BV.
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등록된 정보가 없습니다.
참고문헌 (101)
참고문헌 신청
Miller RA / 1982 / Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody / N Engl J Med 306:517~522
Chiarle R / 1999 / CD30 in normal and neoplastic cells / Clin Immunol 90:157~164
Bartlett NL / 2008 / A phase 1 multidose study of SGN-30 immunotherapy in patients with refractory or recurrent CD30+ hematologic malignancies / Blood 111:1848~1854
Ansell SM / 2007 / Phase I/II study of an anti-CD30 monoclonal antibody(MDX-060)in Hodgkin's lymphoma and anaplastic large-cell lymphoma / J Clin Oncol 25:2764~2769
Senter PD / 2012 / The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma / Nat Biotechnol 30:631~637
Chiarle R / 1999 / CD30 in normal and neoplastic cells / Clin Immunol 90:157~164
Bartlett NL / 2008 / A phase 1 multidose study of SGN-30 immunotherapy in patients with refractory or recurrent CD30+ hematologic malignancies / Blood 111:1848~1854
Ansell SM / 2007 / Phase I/II study of an anti-CD30 monoclonal antibody(MDX-060)in Hodgkin's lymphoma and anaplastic large-cell lymphoma / J Clin Oncol 25:2764~2769
Senter PD / 2012 / The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma / Nat Biotechnol 30:631~637
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