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논문 기본 정보

자료유형
학술저널
저자정보
Lee, Chang Hee (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Yoon, Jin-Young (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Shim, Sung-Eun (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Kim, Jeong Hyun (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Kim, Jun-Yeon (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Kim, Ha-Na (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Hwang, Ji-Min (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Kim, Jung-Hyun (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Goo, Bon Hyuk (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Park, Yeon-Cheol (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine Hospital) Seo, Byung-Kwan (Department of Acupuncture and Moxibustion, Kyung Hee University, Korean Medicine) Baek, Yong-Hyeon Nam, Sang-Soo
저널정보
대한침구의학회 대한침구의학회지 Journal of acupuncture research 제36권 제4호
발행연도
2019.1
수록면
245 - 250 (6page)

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Background: This study was designed to evaluate the clinical safety of Bee Venom (BV) pharmacopuncture at craniofacial acupuncture points. Methods: This was a retrospective study of 108 patients diagnosed with peripheral facial paralysis, trigeminal neuralgia, or facial spasm who were admitted to Kyung Hee University Korean Medicine Hospital at Gangdong, from April 1st, 2017 to August 30th, 2017. Patients were allocated into either, Group 1 (the non-allergy group of patients who did not have an allergic reaction to BV) or Group 2, the group who had allergic reactions to BV. To evaluate the clinical safety of BV pharmacopuncture after each treatment, several criteria were used to measure any side effects: outcome, Common Terminology Criteria for Adverse Events scale, Mueller HL scale, treatment decision after adverse reaction, causality, measures performed for patients with adverse reactions, and efficacy assessment. Results: BV pharmacopuncture delivered in 0.1-0.2 mL at a concentration of 1:30,000 at the craniofacial acupuncture points, showed no statistically significant differences in baseline characteristics between non-allergy Group 1 and allergy Group 2. Amongst the 108 patients, 11 reported side effects after BV pharmacopuncture treatment. These adverse events included rash (n = 7), pruritus (n = 5), swelling (n = 1), vesicles (n = 1), erythema (n = 1), and hives (n = 1). All side effects resolved without sequelae. Conclusion: In this study, BV pharmacopuncture delivered at low doses at the craniofacial acupuncture points, resulted in 10% of patients experiencing non serious side effects suggesting that BV pharmacopuncture was clinically well tolerated.

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