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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 357 - 363 (7page)
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초록· 키워드
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BACKGROUND: Osteoarthritis (OA), the most common arthritis, is one of the most frequently encountered orthopaedic conditions. As a small number of large joints such as knee and hip are affected in OA, OA is an ideal target for local therapy. Although corticosteroid and hyaluronic acid have been traditionally used for joints through intra-articular (IA) injection, IA injection also provides a minimally invasive route to apply cell therapy to treat OA. IA cell therapy has drawn attention because it may provide regeneration of articular cartilage in addition to palliative anti-inflammatory effects. METHODS: Current progress of IA injection therapy and the author’s perspective on this issue are described narratively. RESULTS: It is too premature to have any conclusion on the eventual efficacy of IA cell therapy concerning regeneration of articular cartilage based on current data. Prospective radiological and histological data from larger numbers of patients are needed to prove cost effectiveness of IA cell therapy. CONCLUSIONS: Expanding research in this field will produce further evidences to provide guidance on the eventual effectiveness of IA cell therapy in the future.
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등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
Goldring MB / 2010 / Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis / Ann N Y Acad Sci 1192:230~237
Im GI / 2017 / Clinical use of stem cells in orthopaedics / Eur Cell Mater 33:183~196
Caldwell JR / 1996 / Intra-articular corticosteroids. Guide to selection and indications for use / Drugs 52:507~514
Abramson S. / 2006 / Drug delivery in degenerative joint disease: where we are and where to go? / Adv Drug Deliv Rev 58:125~127
Neander G / 1992 / Pharmacokinetics of intraarticular indomethacin in patients with osteoarthritis / Eur J Clin Pharmacol 42:301~305
Im GI / 2017 / Clinical use of stem cells in orthopaedics / Eur Cell Mater 33:183~196
Caldwell JR / 1996 / Intra-articular corticosteroids. Guide to selection and indications for use / Drugs 52:507~514
Abramson S. / 2006 / Drug delivery in degenerative joint disease: where we are and where to go? / Adv Drug Deliv Rev 58:125~127
Neander G / 1992 / Pharmacokinetics of intraarticular indomethacin in patients with osteoarthritis / Eur J Clin Pharmacol 42:301~305
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