지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background: The risk of transfusion-transmissible infections (TTIs) of HBV, HCV, and HIV in Korea has been reduced significantly by strengthening the blood safety policies. On the other hand, the risk of TTI still exists due to the diagnostic window period or viral variants. Methods: The residual risks of TTI of HBV, HCV, and HIV were calculated from July 1, 2012 to June 30, 2018 by dividing the data into two year sets. The residual risk was conducted by separating the donors who donated only once and those who donated more than once during each period. Results: In the first two years, the residual risks of HBV, HCV, and HIV were calculated to be 17.54/106, 0.42/106, and 0.30/106 respectively. The residual risk of HBV and HCV over the last two years was calculated to be 9.41/106 and 0.27/106, showing a tendency to decrease with time. On the other hand, the residual risk of HIV over the last two years was calculated to be 0.29/106, showing no significant difference. The residual risk in the donors who donated only once was higher than that in the donors who donated more than once during each period. Conclusion: The real transfusion-transmitted infection can be different from the estimated residual risk in this study because this study was based on the thesis that all NAT-reactive blood components cause infection. Because the residual risk of HBV is higher than HCV and HIV, it was considered that the safety measures for the HBV need to be improved continuously. (Korean J Blood Transfus 2019;30:156-162)
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
WHO Expert Committee on Biological Standardization / 2017 / Guidelines on estimation of residual risk of HIV, HBV or HCV infections via cellular blood components and plasma :34
Schmidt M / 2009 / First transmission of human immunodeficiency virus Type 1 by a cellular blood product after mandatory nucleic acid screening in Germany / Transfusion 49:1836~1844
Kim MJ / 2012 / Residual risk of transfusion-transmitted infection with human immunodeficiency virus, hepatitis C virus, and hepatitis B virus in Korea from 2000through 2010 / BMC Infect Dis 12:160
오덕자 / 2015 / NAT 시행 이후 C형 간염바이러스 수혈감염위험도의 변화 / 대한수혈학회지 26(2):193~203
Schreiber GB / 1996 / The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study / N Engl J Med 334:1685~1690
Schmidt M / 2009 / First transmission of human immunodeficiency virus Type 1 by a cellular blood product after mandatory nucleic acid screening in Germany / Transfusion 49:1836~1844
Kim MJ / 2012 / Residual risk of transfusion-transmitted infection with human immunodeficiency virus, hepatitis C virus, and hepatitis B virus in Korea from 2000through 2010 / BMC Infect Dis 12:160
오덕자 / 2015 / NAT 시행 이후 C형 간염바이러스 수혈감염위험도의 변화 / 대한수혈학회지 26(2):193~203
Schreiber GB / 1996 / The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study / N Engl J Med 334:1685~1690
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