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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 115 - 125 (11page)
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Purpose: This study was conducted to determine the malignancy risk and diagnostic value of various types of nonshadowing echogenic foci (NEF) in the risk stratification of thyroid nodules. Methods: A total of 1,018 consecutive thyroid nodules (≥1 cm) with final diagnoses were included. The presence of NEF was determined and types of NEF were classified according to the presence of a comet tail artifact (CTA), location, and size through a prospective evaluation. The associations with malignancy, malignancy risk, and diagnostic value of various types of NEF were assessed. Results: Intrasolid punctate NEF without CTA was the only type of NEF that was an independent predictor of malignancy (P<0.001). The malignancy risk of intrasolid punctate NEF without CTA was substantially higher in solid hypoechoic nodules than in isoechoic or nonsolid nodules (71.3% vs. 9.2%, P<0.001). In solid hypoechoic nodules, slightly increased sensitivity (70.8% vs. 67.9%) for malignancy and a similar malignancy risk (71.4% vs. 71.3%) were observed for intrasolid punctate NEF (with or without CTA) and intrasolid punctate NEF without CTA, respectively. NEF with CTA at the margin of the cystic component was not associated with malignancy or benignity in nonsolid nodules (P>0.05). Conclusion: Intrasolid punctate NEF without CTA was the only independent predictor of malignancy. However, solid hypoechoic nodules with intrasolid punctate NEF should be classified as high-suspicion nodules regardless of coexisting CTA. Other types of NEF had no added value for detecting malignancy compared to intrasolid punctate NEF without CTA.
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참고문헌 (24)
참고문헌 신청
Brito JP / 2014 / The accuracy of thyroid nodule ultrasound to predict thyroid cancer: systematic review and meta-analysis / J Clin Endocrinol Metab 99:1253~1263
Campanella P / 2014 / Quantification of cancer risk of each clinical and ultrasonographic suspicious feature of thyroid nodules: a systematic review and meta-analysis / Eur J Endocrinol 170:R203~R211
Remonti LR / 2015 / Thyroid ultrasound features and risk of carcinoma: a systematic review and meta-analysis of observational studies / Thyroid 25:538~550
Na DG / 2016 / Thyroid Imaging Reporting and Data System risk stratification of thyroid nodules: categorization based on solidity and echogenicity / Thyroid 26:562~572
신정희 / 2016 / Ultrasonography Diagnosis and Imaging-Based Management of Thyroid Nodules: Revised Korean Society of Thyroid Radiology Consensus Statement and Recommendations / Korean Journal of Radiology 17(3):370~395
Campanella P / 2014 / Quantification of cancer risk of each clinical and ultrasonographic suspicious feature of thyroid nodules: a systematic review and meta-analysis / Eur J Endocrinol 170:R203~R211
Remonti LR / 2015 / Thyroid ultrasound features and risk of carcinoma: a systematic review and meta-analysis of observational studies / Thyroid 25:538~550
Na DG / 2016 / Thyroid Imaging Reporting and Data System risk stratification of thyroid nodules: categorization based on solidity and echogenicity / Thyroid 26:562~572
신정희 / 2016 / Ultrasonography Diagnosis and Imaging-Based Management of Thyroid Nodules: Revised Korean Society of Thyroid Radiology Consensus Statement and Recommendations / Korean Journal of Radiology 17(3):370~395
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