지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.11
- 수록면
- 731 - 737 (7page)
이용수
이 논문의 연구 히스토리 (4)
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Background: The number of primary human immunodeficiency virus (HIV)-1 non-B subtype infections (non-B) and that of reports regarding the differences in the pathogenesis of subtype B and non-B infections are increasing. However, to the best of our knowledge, there have been no reports on gross deletion in the nef gene (gΔnef) in non-B infections.
Methods: To determine whether there is a difference in the change in CD4<SUP>+</SUP> T cells after treatment with Korean Red Ginseng (KRG) between patients with subtype B and non-B infections, we retrospectively analyzed and compared the annual decrease in CD4<SUP>+</SUP> T cells (AD) and the proportion of gΔnef in 77 patients who were followed for more than 10 years in the absence of combination antiretroviral therapy.
Results: Overall, AD was significantly faster in patients with non-B infections than in those with subtype B infections. Survival analysis showed that the survival probability was significantly higher in subtype B than in non B-infected patients. These differences mainly resulted from significant differences in the amount of KRG and age. In the patients treated with KRG, there was a significant correlation between the amount of KRG and the AD in both subtypes. Interestingly, there was a significant correlation between the amount of KRG and the proportion of gΔnef in patients infected with subtype B, but not in those infected with non-B. The same phenomenon was observed when the KRG dose was adjusted.
Conclusion: Our results suggest that non-B may be biologically more stable than subtype B.
Methods: To determine whether there is a difference in the change in CD4<SUP>+</SUP> T cells after treatment with Korean Red Ginseng (KRG) between patients with subtype B and non-B infections, we retrospectively analyzed and compared the annual decrease in CD4<SUP>+</SUP> T cells (AD) and the proportion of gΔnef in 77 patients who were followed for more than 10 years in the absence of combination antiretroviral therapy.
Results: Overall, AD was significantly faster in patients with non-B infections than in those with subtype B infections. Survival analysis showed that the survival probability was significantly higher in subtype B than in non B-infected patients. These differences mainly resulted from significant differences in the amount of KRG and age. In the patients treated with KRG, there was a significant correlation between the amount of KRG and the AD in both subtypes. Interestingly, there was a significant correlation between the amount of KRG and the proportion of gΔnef in patients infected with subtype B, but not in those infected with non-B. The same phenomenon was observed when the KRG dose was adjusted.
Conclusion: Our results suggest that non-B may be biologically more stable than subtype B.
목차
ABSTRACT
1. Introduction
2. Materials and methods
3. Results
4. Discussion
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Impact of HIV-1 subtype and Korean Red Ginseng on AIDS progression: comparison of subtype B and subtype D
Journal of Ginseng Research
2019 .04
-
Genetic defects in the nef gene are associated with Korean Red Ginseng intake : monitoring of nef sequence polymorphisms over 20 years
Journal of Ginseng Research
2017 .04
-
Outcome Differences by Delirium Motor Subtype in Patients with Ischemic Stroke
PSYCHIATRY INVESTIGATION
2019 .01
-
The HIV-1 Virulence Factor Nef as a New Therapeutic Target Against HIV/AIDS
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2020 .09
-
Korean Red Ginseng water extract arrests growth of xenografted lymphoma cells
Journal of Ginseng Research
2016 .10
-
Effect of Korean Red Ginseng extracts on drug-drug interactions
Journal of Ginseng Research
2018 .06
-
The effects of Korean Red Ginseng on stress-related neurotransmitters and gene expression: A randomized, double-blind, placebo-controlled trial
Journal of Ginseng Research
2023 .11
-
Immuno-enhancement effects of Korean Red Ginseng in healthy adults: a randomized, double-blind, placebo-controlled trial
Journal of Ginseng Research
2021 .01
-
Molecular subtypes and imaging phenotypes of breast cancer
ULTRASONOGRAPHY
2016 .01
-
Integrative multi-omics profiling of resectable pancreatic cancer reveals clinically relevant molecular subtypes with precision strategies beyond the clinical staging system
대한임상종양학회 학술대회지
2021 .06
-
Proteomic studies of putative molecular signatures for biological effects by Korean Red Ginseng
Journal of Ginseng Research
2019 .10
-
Investigation of the Subtypes of Nonsuicidal Self-Injury Based on the Forms of Self-Harm Behavior: Examining Validity and Utility via Latent Class Analysis and Ecological Momentary Assessment
Journal of Korean Medical Science
2023 .05
-
Anti-aging effects of Korean Red Ginseng (KRG) in differentiated embryo chondrocyte (DEC) knockout mice
Journal of Ginseng Research
2021 .01
-
Safety and antifatigue effect of Korean Red Ginseng: a randomized, double-blind, and placebo-controlled clinical trial
Journal of Ginseng Research
2019 .10
-
The Beneficial Effect of Korean Red Ginseng Extract on Atopic Dermatitis Patients: An 8 Weeks Open, Noncomparative Clinical Study
Annals of Dermatology
2018 .01
-
Radiologic Subtypes and Treatment Outcome of Unclassifiable Type Mycobacterium avium Complex Pulmonary Disease
Journal of Korean Medical Science
2023 .01
-
Clinical Implication of Maumgyeol Basic Biotypes–Electroencephalography- and Photoplethysmogram-Based Bwave State Inventory
PSYCHIATRY INVESTIGATION
2024 .05
-
Korean Red Ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation
Journal of Ginseng Research
2023 .07
-
The Effect of Korean Red Ginseng on Symptoms and Quality of Life in Chronic Tinnitus: A Randomized, Open-Label Pilot Study
Journal of Audiology & Otology
2015 .01
-
Effect of Korean Red Ginseng treatment on the gene expression profile of diabetic rat retina
Journal of Ginseng Research
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-524-000241804