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논문 기본 정보

자료유형
학술저널
저자정보
김태현 (광주기독교병원)
저널정보
전남대학교 의과학연구소 전남의대학술지 전남의대학술지 제51권 제2호
발행연도
2015.1
수록면
97 - 101 (5page)

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초록· 키워드

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This study aimed to identify factors that affect the size of benign thyroid nodules andto predict nodule size by using a newly developed model. Because most thyroid nodulesare benign, they are commonly only monitored. Only a few studies have evaluated thenatural progression or regression of benign thyroid nodules. Large-scale studies on thesubject are nonexistent. Between January 2001 and December 2011, our study subjectswere selected from among 1,564 patients with benign thyroid nodules (2,469 nodules)in a retrospective analysis. We measured nodule size and volume and attempted to predictnodule size by using a newly developed model. Nodules were considered to haveincreased in size if the total volume increased by >15%. Nodules that increased in sizeover time required a longer follow-up period than nodules that decreased in size. Theproportion of females and the cystic proportion of the nodules were relatively high inour study sample. For thyroid nodules that increased in size, we analyzed potentialpredictive factors. Larger nodule volume, extended follow-up period, and high cysticproportion were positively associated with increased nodule size. According to the modelwe developed in our study, the nodules in the group with an increase in size grewat an approximate rate of 0.034 cm3 per year when controlled for other factors. Percutaneous ethanol injection or radiofrequency ablation is performed for cosmeticpurposes and proper functioning if or when nodules reach a certain size. The modelused in our study may offer helpful insight in determining an optimal treatment schedulefor benign thyroid nodules.

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