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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.1
- 수록면
- 64 - 73 (10page)
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ObjectiveTo evaluate the endometrial histopathological profile of patients undergoing curettage and the association of thehistopathological profile with the pregnancy outcome during the subsequent in-vitro fertilization (IVF) cycle.
MethodsIn this retrospective cohort study, a total of 248 women with at least one failed attempt of IVF and who underwentcurettage and a subsequent IVF were included. Demographic data, endometrial histopathological records, stimulationinformation, and pregnancy outcomes were collected and analyzed.
ResultsThe histopathological analysis of endometrial tissues showed that 130 women (52.4%) had endometrial pathologies.
Of these women, 103 (41.5%) had endometrial polyps, 22 (8.9%) had chronic endometritis, and five (2.0%) had bothpolyps and endometritis. No statistical difference was observed between the normal histopathology group and theabnormal histopathology group in the outcome of the subsequent IVF cycle. Subgroup analyses were performed tofurther characterize and compare women with normal histopathology and women with endometrial polyps (polypsubgroup) or chronic endometritis (endometritis subgroup). No statistical differences were found among the threegroups in the rates of pregnancy (44.1% vs. 49.5% vs. 45.5%, P=0.72), biochemical pregnancy loss (13.5% vs. 15.7% vs.
20.0%, P=0.86), clinical pregnancy loss (25.0% vs. 31.4% vs. 30.0%, P=0.77), and live birth (27.1% vs. 26.2% vs. 22.7%,P=0.91) during the subsequent IVF cycle.
ConclusionWomen with previously failed IVF and abnormal endometrial histopathology treated with curettage had the sameoutcome in the subsequent IVF cycle as women with normal endometrial histopathology.
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