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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 463 - 471 (9page)
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Purpose: To evaluate the overall and segmental oncological and functional outcome of robot-assisted radical cystectomy (RARC) during the learning curve. Materials and Methods: From August 2007 to November 2017, a total of 120 bladder cancer patients were treated with RARC in a single-tertiary hospital. These were divided into three groups of 40 consecutive cases. Overall and subgroup analysis of each group was used to evaluate oncological and functional outcomes throughout the learning curve. Results: Among the 120 RARC cases, 42, 73, and 5 patients received extracorporeal urinary diversion (ECUD), intracorporeal urinary diversion (ICUD), and ureterocutaneostomy, respectively. There was a transition from ECUD to ICUD during the learning curve. The positive surgical margin rate was 0.8%. The mean lymph node yield for the standard and extended pelvic lymph node dissection was 12.5 and 30.1, respectively, and increased to 19.8 and 31.2 and further to 20.0 and 37.9, respectively, with each additional series of 40 cases. The 5-year overall survival and 3-year recurrence-free survival rates were 86.6% and 81.4%, respectively. The 1-year daytime continence rate was 75.7%, while the nighttime continence rate was 51.4%. The potency preservation rate was 66.7% (n=8) with or without phosphodiesterase-5 inhibitors (PDE5-I) at 1 year and 33.3% without PDE5-I (n=4). Conclusions: RARC results in comparable oncological and functional outcomes to open radical cystectomy. In addition, the oncological and functional outcomes were well maintained throughout the learning curve. ECUD transition to ICUD was safe and did not compromise oncological or functional outcome.
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참고문헌 (30)
참고문헌 신청
Shariat SF / 2006 / Outcomes of radical cystectomy for transitional cell carcinoma of the bladder : a contemporary series from the Bladder Cancer Research Consortium / J Urol 176:2414~2422
Challacombe BJ / 2011 / The role of laparoscopic and robotic cystectomy in the management of muscle-invasive bladder cancer with special emphasis on cancer control and complications / Eur Urol 60:767~775
Guiote I / 2016 / Complications from robot-assisted radical cystectomy : where do we stand / Actas Urol Esp 40:108~114
Parekh DJ / 2018 / Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer(RAZOR) : an open-label, randomised, phase 3, non-inferiority trial / Lancet 391:2525~2536
Bochner BH / 2015 / Comparing open radical cystectomy and robot-assisted laparoscopic radical cystectomy : a randomized clinical trial / Eur Urol 67:1042~1050
Challacombe BJ / 2011 / The role of laparoscopic and robotic cystectomy in the management of muscle-invasive bladder cancer with special emphasis on cancer control and complications / Eur Urol 60:767~775
Guiote I / 2016 / Complications from robot-assisted radical cystectomy : where do we stand / Actas Urol Esp 40:108~114
Parekh DJ / 2018 / Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer(RAZOR) : an open-label, randomised, phase 3, non-inferiority trial / Lancet 391:2525~2536
Bochner BH / 2015 / Comparing open radical cystectomy and robot-assisted laparoscopic radical cystectomy : a randomized clinical trial / Eur Urol 67:1042~1050
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