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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 229 - 237 (9page)
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초록· 키워드
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The oncological outcomes of laparoscopic rectal cancer surgery were evaluated in recent multicenter randomized clinical trials (RCTs). The MRC-CLASSIC, COLOR II, and COREAN trials found no differences in local recurrence or diseasefree survival rate between laparoscopic and open surgery. However, the noninferiority of laparoscopic surgery with respect to open surgery for rectal cancer was not established on statistical analysis in the ACOSOG Z6051 and the ALaCaRT trials. Quality of total mesorectal excision (TME) is one of the most important prognostic factors. Incomplete TME had unfavorable oncologic outcomes compared to complete TME. Although TME quality can be clearly identified on pathologic evaluation, there is controversy regarding the acceptable range of oncologically safe TME for laparoscopic surgery. It is not certain whether near-complete TME has an unfavorable oncologic impact and whether laparoscopic surgery with near-complete TME is an oncological threat. Therefore, the surgical community will be interested in the long-term outcomes and meta-analyses of ongoing large-scale RCTs. Laparoscopic rectal cancer surgery has been steadily improving its safety for oncology surgery, which has been reported consistently in various multicenter RCTs. To improve surgical quality, colorectal surgeons should choose the most appropriate surgical technique, including laparoscopic surgery.
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등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Heald RJ / 1982 / The mesorectum in rectal cancer surgery--the clue to pelvic recurrence? / Br J Surg 69:613~616
Nagtegaal ID / 2002 / Macroscopic evaluation of rectal cancer resection specimen : clinical significance of the pathologist in quality control / J Clin Oncol 20:1729~1734
Janson M / 2004 / Randomized clinical trial of the costs of open and laparoscopic surgery for colonic cancer / Br J Surg 91:409~417
Guillou PJ / 2005 / Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer(MRC CLASICC trial) : multicentre, randomised controlled trial / Lancet 365:1718~1726
van der Pas MH / 2013 / Laparoscopic versus open surgery for rectal cancer(COLOR II) : short-term outcomes of a randomised, phase 3 trial / Lancet Oncol 14:210~218
Nagtegaal ID / 2002 / Macroscopic evaluation of rectal cancer resection specimen : clinical significance of the pathologist in quality control / J Clin Oncol 20:1729~1734
Janson M / 2004 / Randomized clinical trial of the costs of open and laparoscopic surgery for colonic cancer / Br J Surg 91:409~417
Guillou PJ / 2005 / Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer(MRC CLASICC trial) : multicentre, randomised controlled trial / Lancet 365:1718~1726
van der Pas MH / 2013 / Laparoscopic versus open surgery for rectal cancer(COLOR II) : short-term outcomes of a randomised, phase 3 trial / Lancet Oncol 14:210~218
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