메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류
인문학
인문학 일반 역사학 철학 종교학 어문학 기타 인문학
사회과학
사회과학 일반 경영학 관광학 교육학 군사학 문헌정보학 법학 사회학 신문방송학 심리과학 정치외교학 지리학 행정학 경제학 무역학 인류학 기타 사회과학
자연과학
자연과학 일반 물리학 생물학 생활과학 수학·통계학 천문학 지구과학 화학 기타 자연과학
공학
공학 일반 건축공학 기계공학 산업공학 재료·에너지공학 전기전자공학 조선해양공학 화학공학 컴퓨터학 기타공학
의약학
의학 일반 간호학 수의학 약학 한의학 기초의학 임상의학 기타 의약학
농수해양학
농수해양학 일반 농학 수산학 식품과학 임학 축산학 해상운송학 기타 농수해양학
예술체육학
예술 일반 디자인 미술 미용 사진 음악학 의상 체육 공연매체예술 기타 예술체육학
복합학
학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

ENG

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Senna Gianenrico (Asthma Center and Allergy Unit Verona University Hospital Verona Italy.) Latorre Manuela (Department of Surgery Medicine and Molecular Biology and Critical Care Nuovo Ospedale Apuano Univer) Bugiani Massimo (Pneumology and Tisiology Unit National Health Service (ASL TO2) Turin Italy.) Caminati Marco (Asthma Center and Allergy Unit Verona University Hospital Verona Italy.) Heffler Enrico (Personalized Medicine Asthma and Allergy Humanitas Clinical and Research Center IRCCS Rozzano Italy) Morrone Daniela (Personalized Medicine Asthma and Allergy Humanitas Clinical and Research Center IRCCS Rozzano Italy) Paoletti Giovanni (Personalized Medicine Asthma and Allergy Humanitas Clinical and Research Center IRCCS Rozzano Italy) Parronchi Paola (Department of Clinical and Experimental MedicineUniversity of Florence Florence Italy.) Puggioni Francesca (Personalized Medicine Asthma and Allergy Humanitas Clinical and Research Center IRCCS Rozzano Italy) Blasi Francesco (Department of Internal Medicine Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Respirato) Canonica Giorgio Walter (Personalized Medicine Asthma and Allergy Humanitas Clinical and Research Center IRCCS Rozzano Italy) Paggiaro Pierluigi (Department of Surgery Medicine and Molecular Biology and Critical Care Nuovo Ospedale Apuano Univer)
저널정보
대한천식알레르기학회(구 대한알레르기학회) Allergy, Asthma & Immunology Research Allergy, Asthma & Immunology Research Vol.13 No.2
발행연도
2021.1
수록면
219 - 228 (10page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Purpose: After adolescence, asthma is more frequent in females than in males due to different hormonal, immunologic, and occupational/environmental factors. The higher prevalence and severity of the disease in females have already been reported in international registries. The aim of this study was to explore the difference in terms of clinical, functional, and biological characteristics between male and female patients with severe asthma in a real-life, registry-based setting. Methods: Baseline data from the Severe Asthma Network in Italy registry were analyzed in 1,123 patients with severe asthma, according to sex. Results: Almost 2/3 of severe asthmatics were female. Late-onset asthma, obesity and gastro-esophageal reflux were more frequent in females than in males, while previous smoking habits and nasal polyposis were more frequent in males. Females had poor asthma control and a higher number of severe exacerbations leading to hospitalization, in comparison to males. Biomarkers of type 2 inflammation (blood eosinophil, exhaled nitric oxide, and serum immunoglobulin E levels) were significantly higher in males than in females. The type 2 profile (defined by a combination of these 3 biomarkers) was significantly more frequent in males than in females. In multivariate analysis, late-onset asthma and a normal body mass index were only independent variables associated with the type 2 profile, while male sex and age showed only a trend toward the association with the type 2 profile. Conclusions: Significant differences may be observed between male and female patients with severe asthma, influencing the asthma pheno-endotyping in both sexes.
#Severe asthma #sex #male #female #type 2 #biomarkers #obesity #smoking

목차

등록된 정보가 없습니다.

참고문헌 (33)

참고문헌 신청
To T / 2012 / Global asthma prevalence in adults : findings from the cross-sectional world health survey / BMC Public Health 12:204 google schola Zein JG / 2019 / Asthma over the adult life course : gender and hormonal influences / Clin Chest Med 40:149~161 google schola 박소영 / 2018 / High Prevalence of Asthma in Elderly Women: Findings From a Korean National Health Database and Adult Asthma Cohort / Allergy, Asthma & Immunology Research 10(4):387~396 google schola Schatz M / 2003 / The relationship of sex to asthma prevalence, health care utilization, and medications in a large managed care organization / Ann Allergy Asthma Immunol 91:553~558 google schola Zein JG / 2016 / Impact of age and sex on outcomes and hospital cost of acute asthma in the United States, 2011–2012 / PLoS One 11:e0157301 google schola

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0