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논문 기본 정보

자료유형
학술저널
저자정보
Woo Hyeonjin (Department of Pediatrics Inha University School of Medicine Inha University Hospital Incheon Korea.) Samra Mona Salem (Department of Pediatrics Inha University School of Medicine Inha University Hospital Incheon Korea.) Lim Dae Hyun (Department of Pediatrics Inha University School of Medicine Inha University Hospital Incheon Korea.) Kim Jeong Hee (Department of Pediatrics Inha University School of Medicine Inha University Hospital Incheon Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.19
발행연도
2021.1
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1 - 13 (13page)

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Background: Most epidemiological studies depend on the subjects' response to asthma symptom questionnaires. Questionnaire-based study for childhood asthma prevalence may overestimate the true prevalence. The aim of this study was to investigate the prevalence of “Current asthma” using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire and methacholine challenge test in Korean children. Methods: Our survey on allergic disease included 4,791 children (age 7–12 years) from 2010 to 2014 in Korean elementary schools. Bronchial hyperresponsiveness (BHR) was defined as provocative concentration of methacholine causing a 20% fall in forced expiratory volume in one second (FEV1) (PC20) ≤ 16 mg/mL. “Current asthma symptoms” was defined as positive response to “Wheezing, current,” “Treatment, current,” or “Exercise, current.” “Current asthma” was defined when the subjects with “Current asthma symptoms” showed BHR on the methacholine challenge test or had less than 70% of predicted FEV1 value. Results: The prevalence of “Wheezing, ever,” “Wheezing, current,” “Diagnosis, ever,” “Treatment, current,” “Exercise, current,” and “Current asthma symptoms” was 19.6%, 6.9%, 10.0%, 3.3%, 3.5%, and 9.6%, respectively, in our cross-sectional study of Korean elementary school students. The prevalence of BHR in elementary school students was 14.5%. The prevalence of BHR in children with “Wheezing, ever,” “Wheezing, current,” “Diagnosis, ever,” “Treatment, current,” and “Exercise, current” was 22.3%, 30.5%, 22.4%, 28.8%, and 29.9%, respectively. BHR was 26.1% in those with “Current asthma symptoms.” The prevalence of “Current asthma” was 2.7%. Conclusions: Our large-scale study provides 2.7% prevalence of current asthma in Korean elementary school children. Since approximately one third of the children who have “Current asthma symptoms” present BHR, both subjective and objective methods are required to accurately predict asthma in subjects with asthma symptoms.
#Asthma #Prevalence #Child #Epidemiology #Questionnaires #Bronchial Hyperresponsiveness

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참고문헌 (40)

참고문헌 신청
Asher MI / 1995 / International study of asthma and allergies in childhood(ISAAC) : rationale and methods / Eur Respir J 8(3):483~491 google schola Cockcroft DW / 1988 / Nonallergic airway responsiveness / J Allergy Clin Immunol 81(1):111~119 google schola Toelle BG / 1992 / Toward a definition of asthma for epidemiology / Am Rev Respir Dis 146(3):633~637 google schola Gruchalla RS / 2003 / Results of an inner-city schoolbased asthma and allergy screening pilot study : a combined approach using written questionnaires and step testing / Ann Allergy Asthma Immunol 90(5):491~499 google schola Yavuz ST / 2011 / Predictive factors for airway hyperresponsiveness in children with respiratory symptoms / Ann Allergy Asthma Immunol 106(5):365~370 google schola

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