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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 634 - 634 (1page)
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Immunomodulation in the local tissue microenvironment plays an important role in macrophage polarization that includes its phenotypic expression and pro-healing function. Here, we demonstrate that a lymph node extracellular matrix (LNEM) derived from porcine lymph node tissues can sufficiently mimic natural lymph node tissue and provide optimal biochemical and biophysical cues for immunomodulation in both two-dimensional (2D) coating system and three-dimensional (3D) hydrogel system. The LNEM with intricate extracellular matrix environment leads to strengthened immunomodulatory effects and a 3D hydrogel system proves to be more effective than 2D coating system. The 3D LNEM induces macro^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10675357');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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