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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 96 - 105 (10page)
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초록· 키워드
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Background and Objectives: Skin aging is reportedly associated with regulation in collagen and elastin synthesis. This study investigated the potential of combining light-emitting diode (LED) treatments using a 630-nm and 850-nm LED with simultaneous microcurrent application. Materials and Methods: The dorsal skin of female pigs was treated with a home-use device. We examined the treatment effects using photography, thermocamera, microscopic pathology, and histological examination to determine the mechanism of action, efficacy, and safety of the procedure. A histological observation was performed using hematoxylin and eosin, Masson’s trichrome, Victoria blue, and immunohistochemical staining. We also used the Sircol soluble collagen and elastin assay kit to measure the amounts of collagen and elastin in the porcine back skin tissue after 2 and 6 weeks. Results: Evaluation by visual inspection and devices showed no skin damage or heat-induced injury at the treatment site. Histological staining revealed that accurate treatment of the targeted dermis layer effectively enhanced collagen and elastin deposition. Collagen type I, a protein defined by immunohistochemical staining, was overexpressed in the early stages of weeks 2 and 6. Combined therapy findings showed the superior capability of the 630-nm and 850-nm LED procedures to induce collagen; in contrast, elastin induction was more pronounced after microcurrent treatments. Conclusion: The home-use LED device, comprising a combination of 630-nm and 850-nm LEDs and microcurrent, is safe and can be used as an adjunctive treatment for self-administered facial rejuvenation.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Benedetto AV / 2019 / What's new in cosmetic dermatology / Dermatol Clin 37:117~128
Clarke LH / 2011 / Aging and the body : a review / Can J Aging 30:495~510
Wang B / 2011 / Photoaging : a review of current concepts of pathogenesis / J Cutan Med Surg 15(Suppl 1):S374~S377
Barolet D / 2009 / Regulation of skin collagen metabolism in vitro using a pulsed 660nm LED light source : clinical correlation with a single-blinded study / J Invest Dermatol 129:2751~2759
Li WH / 2021 / Low-level red plus near infrared lights combination induces expressions of collagen and elastin in human skin in vitro / Int J Cosmet Sci
Clarke LH / 2011 / Aging and the body : a review / Can J Aging 30:495~510
Wang B / 2011 / Photoaging : a review of current concepts of pathogenesis / J Cutan Med Surg 15(Suppl 1):S374~S377
Barolet D / 2009 / Regulation of skin collagen metabolism in vitro using a pulsed 660nm LED light source : clinical correlation with a single-blinded study / J Invest Dermatol 129:2751~2759
Li WH / 2021 / Low-level red plus near infrared lights combination induces expressions of collagen and elastin in human skin in vitro / Int J Cosmet Sci
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