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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background : The global prevalence of type 2 diabetes mellitus (T2DM) is rapidly growing worldwide, and accordingly, the number of patients with concomitant diseases is increasing. Type 2 diabetes mellitus is closely related to nonalcoholic fatty liver disease (NAFLD), and in this study, a meta-analysis was conducted to investigate the effect of dapagliflozin on improving liver enzyme levels in NAFLD patients taking. Methods : This study identified eligible trials based on MeSH terms in the PubMed, EMBASE, and CENTRAL database published from 2012 to March 2020 that reported effects on liver outcomes in patients with type 2 diabetes. The primary outcomes were alanine aminotransferase (ALT), aspartate aminotransferase (AST), and fibrosis-4 (FIB-4) index scores and the second outcomes were body mass index (BMI), and high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels. For the statistical analysis, standardized mean difference (SMD) was calculated at 95% confidence intervals (CIs), and fixed or random-effects models were used to assess the outcomes.
목차
등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
World Health Organization / 2016 / Global Report on Diabetes
Health Insurance Review & Assessment Service / Healthcare Bigdata Hub
Miralles-Linares F / 2012 / Metformininduced hepatotoxicity / Diabetes Care 35(3):e21
김수영 / 2018 / 당뇨병에서의 동반질환 유병률 및 조합유병률 / 보건정보통계학회지 43(3):237~244
Kim S-K / 2014 / Nonalcoholic fatty liver disease is associated with increased carotid intima-media thickness only in type 2 diabetic subjects with insulin resistance / The Journal of Clinical Endocrinology & Metabolism 99(5):1879~1884
Health Insurance Review & Assessment Service / Healthcare Bigdata Hub
Miralles-Linares F / 2012 / Metformininduced hepatotoxicity / Diabetes Care 35(3):e21
김수영 / 2018 / 당뇨병에서의 동반질환 유병률 및 조합유병률 / 보건정보통계학회지 43(3):237~244
Kim S-K / 2014 / Nonalcoholic fatty liver disease is associated with increased carotid intima-media thickness only in type 2 diabetic subjects with insulin resistance / The Journal of Clinical Endocrinology & Metabolism 99(5):1879~1884
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Effect of Dapagliflozin on Alanine Aminotransferase Improvement in Type 2 Diabetes Mellitus with Non-alcoholic Fatty Liver Disease
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제2형 당뇨병 환자에서 Dapagliflozin이 혈당과 심혈관계질환 위험인자에 미치는 영향 및 안전성
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Evaluation and Management of Extrahepatic Manifestations of Nonalcoholic Fatty Liver Disease
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Nonalcoholic fatty liver disease and non-liver comorbidities
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DPP-4 Inhibitor in Type 2 Diabetes Mellitus Patient with Non-Alcoholic Fatty Liver Disease: Achieving Two Goals at Once?
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Non-invasive imaging biomarkers for liver steatosis in non-alcoholic fatty liver disease: present and future
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Causes and risk profiles of mortality among individuals with nonalcoholic fatty liver disease
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Beyond Liver Disease: Non-Alcoholic Fatty Liver Disease and Advanced Liver Fibrosis in Kidney Disease
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Albuminuria Is Associated with Steatosis Burden in Patients with Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease (Diabetes Metab J 2021;45:698-707)
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