지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Acetaminophen or paracetamol (N-acetyl-para-aminophenol [APAP]) is a safe and effective antipyretic and analgesic drug and is a representative nonprescription drug. However, APAP is one of the most common nonprescription drugs used for intentional overdose or suicide, thereby resulting in hundreds of deaths annually in the United States. Moreover, the misuse of nonprescription drugs is a cause of increasing concern in Korea with the revision of the Pharmaceutical Affairs Law in 2012. Generally, the mortality rate of APAP overdose is extremely low due to the well-established treatment guidelines and availability of antidotes. However, it should not be overlooked because of the high number of either accidental or intentional APAP overdose cases recorded every day. To achieve a good prognosis, individuals with APAP overdose must be immediately identified and brought to the hospital. Herein, we report an autopsy case of an individual with APAP overdose who died due to acute liver injury.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Gummin DD / 2019 / 2018 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 36th Annual Report / Clin Toxicol (Phila) 57:1220~1413
Ostapowicz G / 2002 / Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States / Ann Intern Med 137:947~954
Chung SP / 2008 / Acetaminophen poisoning / J Korean Soc Clin Toxicol 6:1~8
Chiew AL / 2020 / Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand / Med J Aust 212:175~183
Bum JH / 2011 / Extended blood drug concentrations in extended release formulated acetaminophen overdose patients / J Korean Soc Clin Toxicol 9:71~76
Ostapowicz G / 2002 / Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States / Ann Intern Med 137:947~954
Chung SP / 2008 / Acetaminophen poisoning / J Korean Soc Clin Toxicol 6:1~8
Chiew AL / 2020 / Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand / Med J Aust 212:175~183
Bum JH / 2011 / Extended blood drug concentrations in extended release formulated acetaminophen overdose patients / J Korean Soc Clin Toxicol 9:71~76
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