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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 166 - 166 (1page)
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Few extracts and single compounds from Ecklonia cava have been reported to exhibit antitumor activity in breast cancer and ovarian cancer, but the effects of a tannin-enriched hot water extract of E. cava (TEE) in colon cancer have not been determined. To recognize the anti-tumor activity of tannin-enriched hot water extract of Ecklonia cava (TEE) against CT26 (colon carcinoma) cells, variations in the tumor growth, histopathological structure, and the molecular mechanism were analyzed in CT26 tumor bearing BALB/cKorl mice, after administration of TEE. This hot water extract contains high levels of total condensed tannin content (326.5 mg/g), and exhibited high inhibitory activity (IC50 = 30.25 mg/ml) against DPPH radicals. In micro CT imaging and weighting analyses, the volume and weight of CT26 tumor was significantly decreased in BALB/cKorl mice with 3 doses of TEE for 37 days without changing the ... 전체 초록 보기
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