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- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 75 - 75 (1page)
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To investigate the anti-tumor activity of tannin-enriched extract of Ecklonia cava (TEE) against colon carcinoma, alterations in the tumor growth, histopathological structure, and the molecular mechanism were analyzed in CT26 tumor bearing BALB/cKorl mice, after administration of TEE. This extract contains high levels of total condensed tannin content (326.5 mg/g), and exhibited high inhibitory activity (IC50 = 30.25 mg/ml) against DPPH radicals. In micro CT imaging and weighting analyses, the volume and weight of CT26 tumor was significantly decreased in C57BL/6NKorl mice with 3 doses of TEE for 32 days without changing the weight of other organs. The analyses of H&E stained tumor sections exhibit significant difference in the extent of cell death regions between TEE t ... 전체 초록 보기
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