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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.5
- 수록면
- 69 - 69 (1page)
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Background : According to WHO cancer report, 1in 6 death is due to cancer. Cancer patients were 18.1million in 2018 and the number of death by cancers is expected to be almost double in 2040. Prostate cancer is the 2nd carcinoma for men. Ginseng has long been widely used as an oriental medical plant in Korea and China. The main compound of ginseng has a very little or none of compound K (C-K) which is in general produced by bio-transformation by some enzymes. C-K effects have been extensively studied and were found to have strong anticancer effects, which was thoroughly proven via in vitro tests. C-K also is known for reducing oxidative stress, anti-inflammation reaction, anti-obesity and myelosuppression. C-K induces the programed cell death through mitochondria-dependent pathway. It also causes a repression of glucose metabolism function. C-K well controls the cell cycle pathways by controlling CD1 and CDK4 proteins in G1 cell cycle stage. C-K also limits the cell proliferation and metastasis by inhibiting those proteins associated with apoptosis. In our study, ... 전체 초록 보기
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