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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 98 - 98 (1page)
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이 논문의 연구 히스토리 (3)
2021
Protective effect of Silibinin on Silica Dioxide-induced inflammation through suppressing TXNIP/MAPKs/AP-1 signaling
Woong-Il Kim
,
Je-Oh Lim
,
Se-jin Lee
외 3명
한국실험동물학회 학술발표대회 논문집
2021.07
학술대회자료
Protective effects of Silibinin on Silica Dioxide-induced inflammation through suppressing TXNIP/MAPKs/AP-1 signaling
Woong-Il Kim
,
Je-Oh Lim
,
Tae-Yang Jung
외 4명
한국실험동물학회 학술발표대회 논문집
2021.01
학술대회자료
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초록· 키워드
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Silica dioxide nanoparticles (siONPs) have been applied to several fields, such as drug delivery and gene therapy. However, SiONPs are a constituent of fine dust and can induce excessive inflammatory responses in the lungs via the airways. Silibinin a major component of silymarin, has been known for its anti-oxidant and anti-inflammatory effects. In the present study, we explored the protective effects of silibinin against SiONPs-induced airway inflammation and explored its underlying mechanism of action, focusing on thioredoxin-interacting protein (TXNIP)/mitogen-activated protein kinase (MAPKs) in vitro and in vivo. In SiONPs-stimulated NCI-H292 airway epithelial cells, silibinin treatment effectively suppressed the elevation of the mRNA expression of tum ... 전체 초록 보기
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Protective effect of Silibinin on Silica Dioxide-induced inflammation through suppressing TXNIP/MAPKs/AP-1 signaling
한국실험동물학회 학술발표대회 논문집
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Silibinin attenuates silica dioxide nanoparticles-induced inflammation by suppressing TXNIP/MAPKs/AP-1 signaling
한국실험동물학회 학술발표대회 논문집
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Silibinin attenuates silica dioxide nanoparticles-induced inflammation by suppressing TXNIP/MAPK/AP-1 signaling
한국실험동물학회 학술발표대회 논문집
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Effect of silibinin in mouse lung inflammation model induced by PM metal components
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Protective Effects of Silibinin and Its Possible Mechanism of Action in Mice Exposed to Chronic Unpredictable Mild Stress
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Silibilin-Induces Apoptosis in Breast Cancer Cells by Modulating p53, p21, Bak and Bcl-xl Pathways
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Silibinin alleviates small intestine damage induced by aerosol inhalation of ammonium sulfate and ammonium nitrate
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Hypoxia Induced High Expression of Thioredoxin Interacting Protein (TXNIP) in Non-small Cell Lung Cancer and its Prognostic Effect
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Titanium dioxide nanoparticles exacerbate allergic airway inflammation via TXNIP upregulation in a mouse model of asthma
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Pulmonary inflammation caused by silica dioxide nanoparticles in mice via TXNIP/NLRP3 signaling pathway
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Preparation, Characterization and Cytotoxicity of Silibinin-Containing Nanoniosomes in T47D Human Breast Carcinoma Cells
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Thioredoxin Interacting Protein Expressed in Osteoblasts Mediates the Anti-Proliferative Effects of High Glucose and Modulates the Expression of Osteocalcin
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[독성병리] Melatonin alleviates silica nanoparticle-induced lung inflammation via thioredoxin-interacting protein downregulation
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2022 .01
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Particulate matters-mediated oxidative stress induces airway inflammation and pulmonary dysfunction through TXNIP/NF-κB and SIRT1/p53/caspase-3 pathways in mice
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UCI(KEPA) : I410-ECN-0101-2021-528-001569958