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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2005.1
- 수록면
- 1,027 - 1,031 (5page)
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초록· 키워드
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In the present study, wogonin, a major flavone isolated from Scutellaria Radix were examined for its imunosuppressive activity on the 2,4-dinitro-fluorobenzene (DNFB)-induced delayed type hypersensitivity (DTH) in C3H/HeN mice. This compound inhibited selectively $TNF-\alpha$ and IL-4, but not IL-6, IL-10 and $IFN-\gamma$ on DNFB-induced Th1 and Th2 cytokines in a concentration-dependent manner. Interestingly, this compound increased the expression of heme oxygenase-1 (HO-1) in a concentration-dependent manner The above results reveal that wogonin possesses anti-inflammatory, humoral and cellular immunomodulatory, and stress reducing activities on the DNFB-induced DTH in mice and these properties may contribute to the anti-atopic dermatitis activity of Scutellaria Radix.
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Immunosuppressive Activity of Wogonin from Scutellaria Radix on DNFB-induced Delayed Type Hypersensitivity in Mice
대한동의병리학회 학술대회논문집
2005 .08
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마우스에서 황금 유래 Wogonin의 Th1과 Th2 사이토가인 조절 효과
동의생리병리학회지
2005 .08
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Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix
대한약학회 학술대회
2001 .01
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$CD4^+$ Jurkat T 세포주에서 Th1과 Th2 사이토가인 조절에 미치는 황금 유래 Baicalin, Baicalein 및 Wogonin의 효과
동의생리병리학회지
2005 .01
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Structure and Antiinflammatory Activity Relationships of Wogonin Derivatives
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
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Suppression of Cyclooxygenase-2 Expression of Skin Fibroblasts by Wogonin, a Plant Flavone from Scutellaria Radix
한국응용약물학회 추계학술발표논문집
2003 .01
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Synthetic Wogonin Derivatives Suppress Lipopolysaccharide-Induced Nitric Oxide Production and Hydrogen Peroxide-Induced Cytotoxicity
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
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Neuroprotective Effect of Wogonin： Potential Roles of Inflammatory Cytokines
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
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Suppression of Cyclooxygenase-2 and inducible Nitric Oxide Synthase Enzyme Induction from Lipopolysaccharide-induced RAW 264.7 by Wogonin, a Plant Flavone from Scutellaria Radix
대한약학회 학술대회
2000 .01
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Wogonin and Its Analogs
대한약학회 학술대회
2003 .01
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Structural Alterations of Wogonin Significantly Reduce the Inhibitory Activity against COX-2 Catalyzed PGE Production from LPS-Induced RAW 264.7 Cells
Biomolecules & Therapeutics(구 응용약물학회지)
2009 .01
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Different Effects of Flavonoids in Scutellaria baicalensis on Anxious and Sedative Behaviors
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2006 .01
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알코올로 유도된 흰쥐의 간 지방 형성에 황금 추출물이 미치는 효과
한방비만학회지
2018 .01
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Inhibition of Contact Dermatitis in Animal Models and Suppression of Proinflammatory Gene Expression by Topically Applied Flavonoid, Wogonin
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
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Histopathological Comparison of Animal Models of Skin Inflammation and Inhibition of the Inflammatory Responses by Plant Flavonoid, Wogonin
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2005 .01
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淸熱潤膚湯이 DNFB로 유발된 알레르기 피부염에 미치는 효과
대한한방내과학회지
2008 .01
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Wogonin inhibits Cytokine-induced TARC/CCL17 Expression by Suppression of NF-${\kappa}B$ activation via p38 MAP kinase Signalning Pathways in HaCaT Keratinocytes
동의생리병리학회지
2007 .01
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Neuroprotective effect of woganin in a rodent model of permanent focal cerebral ischemia
대한약학회 학술대회
2002 .01
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Chondroprotective Effects of Wogonin in Experimental Models of Osteoarthritis in vitro and in vivo
Biomolecules & Therapeutics(구 응용약물학회지)
2015 .01
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