Identification of a Bromodomain-containing Protein 2 (BRD2) Gene Polymorphic Variant and Its Effects on Pork Quality Traits in Berkshire Pigs

Lee, Dong Ju; Hwang, Jung Hye; Ha, Jeongim; Yu, Go Eun; Kwon, Seulgi; Park, Da Hye; Kang, Deok Gyeong; Kim, Tae Wan; Park, Hwa Chun; An, Sang Mi; Kim, Chul Wook

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저자정보: Lee, Dong Ju (Department of Animal Resource Technology, Gyeongnam National University of Science & Technology) Hwang, Jung Hye (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) Ha, Jeongim (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) Yu, Go Eun (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) Kwon, Seulgi (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) Park, Da Hye (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) Kang, Deok Gyeong (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) Kim, Tae Wan (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) Park, Hwa Chun (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) An, Sang Mi (Swine Science and Technology Center, Gyeongnam National University of Science & Technology) Kim, Chul Wook (Department of Animal Resource Technology, Gyeongnam National Univ)

저널정보: 한국축산식품학회 한국축산식품학회지 한국축산식품학회지 제38권 제4호

발행연도: 2018.1

수록면: 703 - 710 (8page)

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Bromodomain-containing protein 2 (BRD2) is a nuclear serine/threonine kinase involved in transcriptional regulation. We investigated the expression and association of the BRD2 gene as a candidate gene for meat quality traits in Berkshire pigs. BRD2 mRNA was expressed at relatively high levels in muscle tissue. Statistical analysis revealed that the c.1709G>C polymorphism of the BRD2 gene was significantly associated with carcass weight, meat color ($a^*$, redness), protein content, cooking loss, water-holding capacity, carcass temperatures 4, 12 and 24 h postmortem, and the 24 h postmortem pH in 384 Berkshire pigs. Therefore, this polymorphism in the porcine BRD2 gene may be used as a candidate genetic marker to improve meat quality traits in pigs.

#bromodomain-containing protein 2 #gene expression #non-synonymous single nucleotide polymorphisms #meat quality #Berkshire pig

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Lee, Dong Ju

소속기관 Department of Animal Resource Technology, Gyeongnam National University of Science & Technology

주요연구분야 농수해양학 > 축산학

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Hwang, Jung Hye