Assessment of the Reliability of a Novel Self-sampling Device for Performing Cervical Sampling in Malaysia

Latiff, Latiffah A.; Rahman, Sabariah Abdul; Wee, Wong Yong; Dashti, Sareh; Asri, Andi Anggeriana Andi; Unit, Nor Hafeeza; Li, Shirliey Foo Siah; Esfehani, Ali Jafarzadeh; Ahmad, Salwana

추천

검색

자료유형: 학술저널

저자정보: Latiff, Latiffah A. (Department of Community Health, Universiti Putra Malaysia, Cancer Resource and Education Centre, Faculty of Medicine and Health Sciences) Rahman, Sabariah Abdul (Department of Pathology, Faculty of Medicine, Universiti Teknology Mara) Wee, Wong Yong (Department of Community Health, Universiti Putra Malaysia, Cancer Resource and Education Centre, Faculty of Medicine and Health Sciences) Dashti, Sareh (Department of Community Health, Universiti Putra Malaysia, Faculty of Medicine and Health Sciences) Asri, Andi Anggeriana Andi (Department of Community Health, Universiti Putra Malaysia, Cancer Resource and Education Centre, Faculty of Medicine and Health Sciences) Unit, Nor Hafeeza (Department of Community Health, Universiti Putra Malaysia, Cancer Resource and Education Centre, Faculty of Medicine and Health Sciences) Li, Shirliey Foo Siah (Department of Community Health, Universiti Putra Malaysia, Cancer Resource and Education Centre, Faculty of Medicine and Health Sciences) Esfehani, Ali Jafarzadeh (Department of Community Health, Universiti Putra Malaysia, Cancer Resource and Education Centre, Faculty of Medicine and Health Sc) Ahmad, Salwana

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제2호

발행연도: 2015.1

수록면: 559 - 564 (6page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Background: The participation of women in cervical cancer screening in Malaysia is low. Self-sampling might be able to overcome this problem. The aim of this study was to assess the reliability of self-sampling for cervical smear in our country. Materials and Methods: This cross-sectional study was conducted on 258 community dwelling women from urban and rural settings who participated in health campaigns. In order to reduce the sampling bias, half of the study population performed the self-sampling prior to the physician sampling while the other half performed the self-sampling after the physician sampling, randomly. Acquired samples were assessed for cytological changes as well as HPV DNA detection. Results: The mean age of the subjects was $40.4{\pm}11.3years$. The prevalence of abnormal cervical changes was 2.7%. High risk and low risk HPV genotypes were found in 4.0% and 2.7% of the subjects, respectively. A substantial agreement was observed between self-sampling and the physician obtained sampling in cytological diagnosis (k=0.62, 95%CI=0.50, 0.74), micro-organism detection (k=0.77, 95%CI=0.66, 0.88) and detection of hormonal status (k=0.75, 95%CI=0.65, 0.85) as well as detection of high risk (k=0.77, 95%CI=0.4, 0.98) and low risk (K=0.77, 95%CI=0.50, 0.92) HPV. Menopausal state was found to be related with 8.39 times more adequate cell specimens for cytology but 0.13 times less adequate cell specimens for virological assessment. Conclusions: This study revealed that self-sampling has a good agreement with physician sampling in detecting HPV genotypes. Self-sampling can serve as a tool in HPV screening while it may be useful in detecting cytological abnormalities in Malaysia.

#Cervical cancer #screening #physician obtained smear #self-sampling #Malaysia

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

Latiff, Latiffah A.

소속기관 Department of Community Health, Faculty of Medicine and Health Science, Universiti Putra Malaysia